Ultrastructural localization of anionic phospholipids in skeletal muscle plasma membrane

M. Moggio, E. Bonilla

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Polymyxin B was used as a probe to label anionic phospholipids in skeletal muscle plasma membrane. This antibiotic produces muscle surface membrane lesions that can be identified in both thin sections and freeze-fracture replicas. The membrane perturbations assumed a patchy distribution with a preferential localization at the level of the I band and A-I bands junction. Intramembraneous particles were also observed within the lesions. We consider the possibility that microdomains of anionic phospholipids in muscle plasma membrane may function in the binding of Ca++.

Original languageEnglish
Pages (from-to)519-523
Number of pages5
JournalHistochemistry
Volume83
Issue number6
DOIs
Publication statusPublished - Nov 1985

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Phospholipids
Skeletal Muscle
Cell Membrane
Polymyxin B
Muscles
Membranes
Anti-Bacterial Agents

ASJC Scopus subject areas

  • Anatomy

Cite this

Ultrastructural localization of anionic phospholipids in skeletal muscle plasma membrane. / Moggio, M.; Bonilla, E.

In: Histochemistry, Vol. 83, No. 6, 11.1985, p. 519-523.

Research output: Contribution to journalArticle

Moggio, M. ; Bonilla, E. / Ultrastructural localization of anionic phospholipids in skeletal muscle plasma membrane. In: Histochemistry. 1985 ; Vol. 83, No. 6. pp. 519-523.
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