Ultrastructural localization of gastric inhibitory polypeptide (GIP) in a well characterized endocrine cell of canine duodenal mucosa

L. Usellini; C. Capella; E. Solcia; A. M J Buchan; J. C. Brown

doi:10.1007/BF00492776

Ultrastructural localization of gastric inhibitory polypeptide (GIP) in a well characterized endocrine cell of canine duodenal mucosa

L. Usellini, C. Capella, E. Solcia, A. M J Buchan, J. C. Brown

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

The polypeptide hormone GIP has been localized ultrastructurally by using specific, monoclonal GIP antibodies and an immunogold technique on aldehyde-osmium fixed specimens of dog duodenal mucosa. A single type of cell showing round, homogeneous, fairly osmiophilic granules with closely applied membrane and a mean size of 188 nm±34 SD has been identified as the GIP cell.

Original language	English
Pages (from-to)	85-89
Number of pages	5
Journal	Histochemistry
Volume	80
Issue number	1
DOIs	https://doi.org/10.1007/BF00492776
Publication status	Published - Jan 1984

ASJC Scopus subject areas

Anatomy

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title = "Ultrastructural localization of gastric inhibitory polypeptide (GIP) in a well characterized endocrine cell of canine duodenal mucosa",

abstract = "The polypeptide hormone GIP has been localized ultrastructurally by using specific, monoclonal GIP antibodies and an immunogold technique on aldehyde-osmium fixed specimens of dog duodenal mucosa. A single type of cell showing round, homogeneous, fairly osmiophilic granules with closely applied membrane and a mean size of 188 nm±34 SD has been identified as the GIP cell.",

author = "L. Usellini and C. Capella and E. Solcia and Buchan, {A. M J} and Brown, {J. C.}",

year = "1984",

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doi = "10.1007/BF00492776",

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AU - Solcia, E.

AU - Buchan, A. M J

AU - Brown, J. C.

PY - 1984/1

Y1 - 1984/1

N2 - The polypeptide hormone GIP has been localized ultrastructurally by using specific, monoclonal GIP antibodies and an immunogold technique on aldehyde-osmium fixed specimens of dog duodenal mucosa. A single type of cell showing round, homogeneous, fairly osmiophilic granules with closely applied membrane and a mean size of 188 nm±34 SD has been identified as the GIP cell.

AB - The polypeptide hormone GIP has been localized ultrastructurally by using specific, monoclonal GIP antibodies and an immunogold technique on aldehyde-osmium fixed specimens of dog duodenal mucosa. A single type of cell showing round, homogeneous, fairly osmiophilic granules with closely applied membrane and a mean size of 188 nm±34 SD has been identified as the GIP cell.

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Ultrastructural localization of gastric inhibitory polypeptide (GIP) in a well characterized endocrine cell of canine duodenal mucosa

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