Ultrastructural localization of motilin in endocrine cells of human and dog intestine by the immunogold technique

L. Usellini, A. M J Buchan, J. M. Polak, C. Capella, M. Cornaggia, E. Solcia

Research output: Contribution to journalArticlepeer-review

Abstract

Motilin-immunoreactivity has been localized by two electron immunocytochemical techniques, using goldlabelled protein A or IgG as second layer, in a specific type of endocrine cell scattered in the epithelium of human and canine upper small intestine. The motilin (M) cell is characterized by relatively small (180 nm in man; 200 nm in the dog), solid granules with homogeneous core and closely applied membrane, round in man, round to irregularly-shaped in the dog. Perinuclear microfilaments are prominent in human motilin cells.

Original languageEnglish
Pages (from-to)363-368
Number of pages6
JournalHistochemistry
Volume81
Issue number4
DOIs
Publication statusPublished - Jul 1984

ASJC Scopus subject areas

  • Anatomy

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