Ultrastructural localization of secretin in endocrine cells of the dog duodenum by the immunogold technique - Comparison with ultrastructurally characterized S cells of various mammals

L. Usellini, C. Capella, B. Frigerio, G. Rindi, E. Solcia

Research output: Contribution to journalArticlepeer-review

Abstract

Secretin has been localized by the immunogold technique in endocrine cells of the dog duodenum - previously described as "K cells" - characterized by secretory granules with double structure consisting of a secretin-containing osmiophilic core surrounded by an argyrophil halo. Granules resembling those of dog secretin cells were also found in some ultrastructurally characterized S cells of the cat, pig, rat and rabbit duodenum, thus confirming in these species the identification of S cells with secretin cells. Conversely, the cells previously described as "S cells" in the dog lacked secretin immunoreactivity.

Original languageEnglish
Pages (from-to)435-441
Number of pages7
JournalHistochemistry
Volume80
Issue number5
DOIs
Publication statusPublished - Sep 1984

ASJC Scopus subject areas

  • Anatomy

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