ASPETTI MORFOLOGICI ULTRASTRUTTURALI DELL'INTERAZIONE FRA MACROFAGI PERITONEALI ED ENDOTOSSINA DI S. TYPHIMURIUM 'IN VIVO' NEL RATTO

Translated title of the contribution: Ultrastructural morphological aspects of the interaction in vivo between peritoneal macrophages and S. typhimurium endotoxin in rat

G. Carosi, E. Magliulo, D. Scevola

Research output: Contribution to journalArticlepeer-review

Abstract

S typhimurium lipopolysccharide conjugated with uranyl acetate in rat peritoneal macrophages was investigated by electron microscopy. The lipopolysaccharide was absorbed into the cell surface and engulfed by micropinocytosis; activation of cytoplasmic structures and the fusion of pinocytotic vacuoles with lysosomal granules having endotoxin degradation then ensued. These morphologic phenomena are discussed in relation to present knowledge on mechanisms of phagocyte function, macrophage activation and RES endotoxin interactions.

Translated title of the contributionUltrastructural morphological aspects of the interaction in vivo between peritoneal macrophages and S. typhimurium endotoxin in rat
Original languageItalian
Pages (from-to)62-66
Number of pages5
JournalGiornale di Malattie Infettive e Parassitarie
Volume27
Issue number1
Publication statusPublished - 1975

ASJC Scopus subject areas

  • Parasitology

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