ASPETTI MORFOLOGICI ULTRASTRUTTURALI DELL'INTERAZIONE FRA MACROFAGI PERITONEALI ED ENDOTOSSINA DI S. TYPHIMURIUM 'IN VIVO' NEL RATTO

G. Carosi; E. Magliulo; D. Scevola

ASPETTI MORFOLOGICI ULTRASTRUTTURALI DELL'INTERAZIONE FRA MACROFAGI PERITONEALI ED ENDOTOSSINA DI S. TYPHIMURIUM 'IN VIVO' NEL RATTO

Translated title of the contribution: Ultrastructural morphological aspects of the interaction in vivo between peritoneal macrophages and S. typhimurium endotoxin in rat

G. Carosi, E. Magliulo, D. Scevola

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

S typhimurium lipopolysccharide conjugated with uranyl acetate in rat peritoneal macrophages was investigated by electron microscopy. The lipopolysaccharide was absorbed into the cell surface and engulfed by micropinocytosis; activation of cytoplasmic structures and the fusion of pinocytotic vacuoles with lysosomal granules having endotoxin degradation then ensued. These morphologic phenomena are discussed in relation to present knowledge on mechanisms of phagocyte function, macrophage activation and RES endotoxin interactions.

Translated title of the contribution	Ultrastructural morphological aspects of the interaction in vivo between peritoneal macrophages and S. typhimurium endotoxin in rat
Original language	Italian
Pages (from-to)	62-66
Number of pages	5
Journal	Giornale di Malattie Infettive e Parassitarie
Volume	27
Issue number	1
Publication status	Published - 1975

ASJC Scopus subject areas

Parasitology

Cite this

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title = "ASPETTI MORFOLOGICI ULTRASTRUTTURALI DELL'INTERAZIONE FRA MACROFAGI PERITONEALI ED ENDOTOSSINA DI S. TYPHIMURIUM 'IN VIVO' NEL RATTO",

abstract = "S typhimurium lipopolysccharide conjugated with uranyl acetate in rat peritoneal macrophages was investigated by electron microscopy. The lipopolysaccharide was absorbed into the cell surface and engulfed by micropinocytosis; activation of cytoplasmic structures and the fusion of pinocytotic vacuoles with lysosomal granules having endotoxin degradation then ensued. These morphologic phenomena are discussed in relation to present knowledge on mechanisms of phagocyte function, macrophage activation and RES endotoxin interactions.",

author = "G. Carosi and E. Magliulo and D. Scevola",

year = "1975",

language = "Italian",

volume = "27",

pages = "62--66",

journal = "Giornale di Malattie Infettive e Parassitarie",

issn = "0017-0321",

publisher = "U T E T SpA",

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T1 - ASPETTI MORFOLOGICI ULTRASTRUTTURALI DELL'INTERAZIONE FRA MACROFAGI PERITONEALI ED ENDOTOSSINA DI S. TYPHIMURIUM 'IN VIVO' NEL RATTO

AU - Carosi, G.

AU - Magliulo, E.

AU - Scevola, D.

PY - 1975

Y1 - 1975

N2 - S typhimurium lipopolysccharide conjugated with uranyl acetate in rat peritoneal macrophages was investigated by electron microscopy. The lipopolysaccharide was absorbed into the cell surface and engulfed by micropinocytosis; activation of cytoplasmic structures and the fusion of pinocytotic vacuoles with lysosomal granules having endotoxin degradation then ensued. These morphologic phenomena are discussed in relation to present knowledge on mechanisms of phagocyte function, macrophage activation and RES endotoxin interactions.

AB - S typhimurium lipopolysccharide conjugated with uranyl acetate in rat peritoneal macrophages was investigated by electron microscopy. The lipopolysaccharide was absorbed into the cell surface and engulfed by micropinocytosis; activation of cytoplasmic structures and the fusion of pinocytotic vacuoles with lysosomal granules having endotoxin degradation then ensued. These morphologic phenomena are discussed in relation to present knowledge on mechanisms of phagocyte function, macrophage activation and RES endotoxin interactions.

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M3 - Articolo

AN - SCOPUS:0016631150

VL - 27

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EP - 66

JO - Giornale di Malattie Infettive e Parassitarie

JF - Giornale di Malattie Infettive e Parassitarie

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ASPETTI MORFOLOGICI ULTRASTRUTTURALI DELL'INTERAZIONE FRA MACROFAGI PERITONEALI ED ENDOTOSSINA DI S. TYPHIMURIUM 'IN VIVO' NEL RATTO

Abstract

ASJC Scopus subject areas

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