Abstract

Treatment of chronic HCV infection with direct acting antivirals can achieve high rates of sustained viral response in persons with HIV. In the perspective of HCV elimination in this population, high rates of HCV detection will be needed. We evaluated the unawareness of HCV infection in 2927 persons newly diagnosed with HIV during 2004–2015 in Rome, Italy. Two-hundred-fifty persons (8.5%) were anti-HCV positive. The proportion of HCV-unaware individuals at the time of HIV diagnosis was 58.0% (145/250), without significant variations over time, 17.2% showed an advanced fibrosis stage. The absence of previous HIV testing was significantly associated with HCV unawareness.

Original languageEnglish
Pages (from-to)1-5
Number of pages5
JournalJournal of Infection and Public Health
DOIs
Publication statusPublished - Jan 1 2019

Fingerprint

HIV
Infection
Italy
Antiviral Agents
Fibrosis
Population

Keywords

  • HCV
  • Hepatitis
  • HIV-HCV coinfection
  • Italy
  • Late diagnosis

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

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title = "Unawareness of HCV serostatus among persons newly diagnosed with HIV",
abstract = "Treatment of chronic HCV infection with direct acting antivirals can achieve high rates of sustained viral response in persons with HIV. In the perspective of HCV elimination in this population, high rates of HCV detection will be needed. We evaluated the unawareness of HCV infection in 2927 persons newly diagnosed with HIV during 2004–2015 in Rome, Italy. Two-hundred-fifty persons (8.5{\%}) were anti-HCV positive. The proportion of HCV-unaware individuals at the time of HIV diagnosis was 58.0{\%} (145/250), without significant variations over time, 17.2{\%} showed an advanced fibrosis stage. The absence of previous HIV testing was significantly associated with HCV unawareness.",
keywords = "HCV, Hepatitis, HIV-HCV coinfection, Italy, Late diagnosis",
author = "Paola Scognamiglio and Assunta Navarra and Nicoletta Orchi and {De Carli}, Gabriella and Silvia Pittalis and Ilaria Mastrorosa and {Visco Comandini}, Ubaldo and Chiara Agrati and Andrea Antinori and Vincenzo Puro and Giuseppe Ippolito and Enrico Girardi",
year = "2019",
month = "1",
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doi = "10.1016/j.jiph.2019.01.055",
language = "English",
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journal = "Journal of Infection and Public Health",
issn = "1876-0341",
publisher = "Elsevier BV",

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TY - JOUR

T1 - Unawareness of HCV serostatus among persons newly diagnosed with HIV

AU - Scognamiglio, Paola

AU - Navarra, Assunta

AU - Orchi, Nicoletta

AU - De Carli, Gabriella

AU - Pittalis, Silvia

AU - Mastrorosa, Ilaria

AU - Visco Comandini, Ubaldo

AU - Agrati, Chiara

AU - Antinori, Andrea

AU - Puro, Vincenzo

AU - Ippolito, Giuseppe

AU - Girardi, Enrico

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Treatment of chronic HCV infection with direct acting antivirals can achieve high rates of sustained viral response in persons with HIV. In the perspective of HCV elimination in this population, high rates of HCV detection will be needed. We evaluated the unawareness of HCV infection in 2927 persons newly diagnosed with HIV during 2004–2015 in Rome, Italy. Two-hundred-fifty persons (8.5%) were anti-HCV positive. The proportion of HCV-unaware individuals at the time of HIV diagnosis was 58.0% (145/250), without significant variations over time, 17.2% showed an advanced fibrosis stage. The absence of previous HIV testing was significantly associated with HCV unawareness.

AB - Treatment of chronic HCV infection with direct acting antivirals can achieve high rates of sustained viral response in persons with HIV. In the perspective of HCV elimination in this population, high rates of HCV detection will be needed. We evaluated the unawareness of HCV infection in 2927 persons newly diagnosed with HIV during 2004–2015 in Rome, Italy. Two-hundred-fifty persons (8.5%) were anti-HCV positive. The proportion of HCV-unaware individuals at the time of HIV diagnosis was 58.0% (145/250), without significant variations over time, 17.2% showed an advanced fibrosis stage. The absence of previous HIV testing was significantly associated with HCV unawareness.

KW - HCV

KW - Hepatitis

KW - HIV-HCV coinfection

KW - Italy

KW - Late diagnosis

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