Uncommon clinical presentation of a lymphocytic lymphoma of intermediate differentiation in a patient with systemic sclerosis

L. Baldini; A. Guffanti; A. Ferrari; D. Castagnone; B. Mascagni; N. Fracchiolla; M. Colombi; A. T. Maiolo

Uncommon clinical presentation of a lymphocytic lymphoma of intermediate differentiation in a patient with systemic sclerosis

L. Baldini, A. Guffanti, A. Ferrari, D. Castagnone, B. Mascagni, N. Fracchiolla, M. Colombi, A. T. Maiolo

Research output: Contribution to journal › Article › peer-review

Abstract

The association of systemic sclerosis (SSc) and non-Hodgkin lymphoma is a rare event and its pathogenetic mechanism remains to be clarified. We describe a previously unreported association of SSc with a lymphocytic lymphoma of intermediate differentiation (IDL), involving the gastrointestinal tract, gallbladder and one salivary gland. Whereas the morphological, immunological and cytogenetic features were typical of IDL, the extensive extranodal involvement and the association with an autoimmune disorder were suggestive of two other lymphomas of mantle lineage: mucosa- associated lymphoid tissue (MALT) lymphoma and monocytoid B-cell lymphoma (MBCL).

Original language	English
Pages (from-to)	657-658
Number of pages	2
Journal	British Journal of Haematology
Volume	86
Issue number	3
Publication status	Published - 1994

Keywords

lymphocytic lymphoma of intermediate differentiation
mantle-zone lymphomas
systemic sclerosis

ASJC Scopus subject areas

Hematology

Cite this

Uncommon clinical presentation of a lymphocytic lymphoma of intermediate differentiation in a patient with systemic sclerosis. / Baldini, L.; Guffanti, A.; Ferrari, A.; Castagnone, D.; Mascagni, B.; Fracchiolla, N.; Colombi, M.; Maiolo, A. T.

In: British Journal of Haematology, Vol. 86, No. 3, 1994, p. 657-658.

Research output: Contribution to journal › Article › peer-review

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AU - Baldini, L.

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AU - Mascagni, B.

AU - Fracchiolla, N.

AU - Colombi, M.

AU - Maiolo, A. T.

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AB - The association of systemic sclerosis (SSc) and non-Hodgkin lymphoma is a rare event and its pathogenetic mechanism remains to be clarified. We describe a previously unreported association of SSc with a lymphocytic lymphoma of intermediate differentiation (IDL), involving the gastrointestinal tract, gallbladder and one salivary gland. Whereas the morphological, immunological and cytogenetic features were typical of IDL, the extensive extranodal involvement and the association with an autoimmune disorder were suggestive of two other lymphomas of mantle lineage: mucosa- associated lymphoid tissue (MALT) lymphoma and monocytoid B-cell lymphoma (MBCL).

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Uncommon clinical presentation of a lymphocytic lymphoma of intermediate differentiation in a patient with systemic sclerosis

Abstract

Keywords

ASJC Scopus subject areas

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