Uncommon clinical presentation of a lymphocytic lymphoma of intermediate differentiation in a patient with systemic sclerosis

L. Baldini, A. Guffanti, A. Ferrari, D. Castagnone, B. Mascagni, N. Fracchiolla, M. Colombi, A. T. Maiolo

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

The association of systemic sclerosis (SSc) and non-Hodgkin lymphoma is a rare event and its pathogenetic mechanism remains to be clarified. We describe a previously unreported association of SSc with a lymphocytic lymphoma of intermediate differentiation (IDL), involving the gastrointestinal tract, gallbladder and one salivary gland. Whereas the morphological, immunological and cytogenetic features were typical of IDL, the extensive extranodal involvement and the association with an autoimmune disorder were suggestive of two other lymphomas of mantle lineage: mucosa- associated lymphoid tissue (MALT) lymphoma and monocytoid B-cell lymphoma (MBCL).

Original languageEnglish
Pages (from-to)657-658
Number of pages2
JournalBritish Journal of Haematology
Volume86
Issue number3
Publication statusPublished - 1994

Fingerprint

Mantle-Cell Lymphoma
Systemic Scleroderma
Marginal Zone B-Cell Lymphoma
B-Cell Lymphoma
Gallbladder
Salivary Glands
Cytogenetics
Non-Hodgkin's Lymphoma
Gastrointestinal Tract
Lymphoma

Keywords

  • lymphocytic lymphoma of intermediate differentiation
  • mantle-zone lymphomas
  • systemic sclerosis

ASJC Scopus subject areas

  • Hematology

Cite this

Uncommon clinical presentation of a lymphocytic lymphoma of intermediate differentiation in a patient with systemic sclerosis. / Baldini, L.; Guffanti, A.; Ferrari, A.; Castagnone, D.; Mascagni, B.; Fracchiolla, N.; Colombi, M.; Maiolo, A. T.

In: British Journal of Haematology, Vol. 86, No. 3, 1994, p. 657-658.

Research output: Contribution to journalArticle

Baldini, L. ; Guffanti, A. ; Ferrari, A. ; Castagnone, D. ; Mascagni, B. ; Fracchiolla, N. ; Colombi, M. ; Maiolo, A. T. / Uncommon clinical presentation of a lymphocytic lymphoma of intermediate differentiation in a patient with systemic sclerosis. In: British Journal of Haematology. 1994 ; Vol. 86, No. 3. pp. 657-658.
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