Abstract
The association of systemic sclerosis (SSc) and non-Hodgkin lymphoma is a rare event and its pathogenetic mechanism remains to be clarified. We describe a previously unreported association of SSc with a lymphocytic lymphoma of intermediate differentiation (IDL), involving the gastrointestinal tract, gallbladder and one salivary gland. Whereas the morphological, immunological and cytogenetic features were typical of IDL, the extensive extranodal involvement and the association with an autoimmune disorder were suggestive of two other lymphomas of mantle lineage: mucosa- associated lymphoid tissue (MALT) lymphoma and monocytoid B-cell lymphoma (MBCL).
| Original language | English |
|---|---|
| Pages (from-to) | 657-658 |
| Number of pages | 2 |
| Journal | British Journal of Haematology |
| Volume | 86 |
| Issue number | 3 |
| Publication status | Published - 1994 |
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Keywords
- lymphocytic lymphoma of intermediate differentiation
- mantle-zone lymphomas
- systemic sclerosis
ASJC Scopus subject areas
- Hematology
Cite this
Uncommon clinical presentation of a lymphocytic lymphoma of intermediate differentiation in a patient with systemic sclerosis. / Baldini, L.; Guffanti, A.; Ferrari, A.; Castagnone, D.; Mascagni, B.; Fracchiolla, N.; Colombi, M.; Maiolo, A. T.
In: British Journal of Haematology, Vol. 86, No. 3, 1994, p. 657-658.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Uncommon clinical presentation of a lymphocytic lymphoma of intermediate differentiation in a patient with systemic sclerosis
AU - Baldini, L.
AU - Guffanti, A.
AU - Ferrari, A.
AU - Castagnone, D.
AU - Mascagni, B.
AU - Fracchiolla, N.
AU - Colombi, M.
AU - Maiolo, A. T.
PY - 1994
Y1 - 1994
N2 - The association of systemic sclerosis (SSc) and non-Hodgkin lymphoma is a rare event and its pathogenetic mechanism remains to be clarified. We describe a previously unreported association of SSc with a lymphocytic lymphoma of intermediate differentiation (IDL), involving the gastrointestinal tract, gallbladder and one salivary gland. Whereas the morphological, immunological and cytogenetic features were typical of IDL, the extensive extranodal involvement and the association with an autoimmune disorder were suggestive of two other lymphomas of mantle lineage: mucosa- associated lymphoid tissue (MALT) lymphoma and monocytoid B-cell lymphoma (MBCL).
AB - The association of systemic sclerosis (SSc) and non-Hodgkin lymphoma is a rare event and its pathogenetic mechanism remains to be clarified. We describe a previously unreported association of SSc with a lymphocytic lymphoma of intermediate differentiation (IDL), involving the gastrointestinal tract, gallbladder and one salivary gland. Whereas the morphological, immunological and cytogenetic features were typical of IDL, the extensive extranodal involvement and the association with an autoimmune disorder were suggestive of two other lymphomas of mantle lineage: mucosa- associated lymphoid tissue (MALT) lymphoma and monocytoid B-cell lymphoma (MBCL).
KW - lymphocytic lymphoma of intermediate differentiation
KW - mantle-zone lymphomas
KW - systemic sclerosis
UR - http://www.scopus.com/inward/record.url?scp=0028308896&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028308896&partnerID=8YFLogxK
M3 - Article
VL - 86
SP - 657
EP - 658
JO - British Journal of Haematology
JF - British Journal of Haematology
SN - 0007-1048
IS - 3
ER -