Uncommon Histopathological Variants of Malignant Melanoma. Part 2

Andrea Saggini, Carlo Cota, Viviana Lora, Heinz Kutzner, Arno Rütten, Omar Sangüeza, Luis Requena, Lorenzo Cerroni

Research output: Contribution to journalReview article


Despite new horizons opened by recent advances in molecular pathology, histological evaluation still remains the diagnostic gold standard regarding cutaneous melanocytic neoplasms. Several histological variants of melanoma have been described, and their knowledge is crucial for accurate diagnosis and classification of cases with unusual clinico-pathological features. Uncommon histological variants of melanoma have been described based on a broad constellation of features, including architectural pattern, stromal alterations, cytological attributes, and other morphological properties. This review is aimed at providing an extensive discussion of unusual but distinctive histopathological variants of melanoma.

Original languageEnglish
Pages (from-to)321-342
Number of pages22
JournalThe American Journal of dermatopathology
Issue number5
Publication statusPublished - May 1 2019


ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Dermatology

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