Undersized annuloplasty for functional mitral regurgitation: Is it responsible for clinically relevant mitral stenosis during exercise?

Antonio Grimaldi, Michele De Bonis, Federico Pappalardo, Maurizio Taramasso, Alessandro Verzini, MariaChiara Calabrese, Francesco Maisano, Ottavio Alfieri

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Background and aim of the study: The study aim was to assess if an undersized mitral annuloplasty for functional mitral regurgitation (FMR) in dilated cardiomyopathy can determine a clinically relevant mitral stenosis during exercise. Methods: Both, rest and stress echocardiography were performed in 12 patients submitted to an undersized ring annuloplasty for FMR in dilated cardiomyopathy. The mean ring size was 27 ± 1.3 mm. All patients were in NYHA functional classes I-II, were in stable sinus rhythm, and without significant residual mitral regurgitation (grade ≤2/4). Results: At peak exercise (mean 81 ± 12 W), the main cardiac performance indices were significantly improved, including systolic blood pressure (121 ± 5.6 versus 169 ± 14 mmHg, p 2, p = 0.05). Although the transmitral mean gradient was increased from 3.2 ± 1.2 to 6.3 ± 2.3 mmHg (p

Original languageEnglish
Pages (from-to)446-453
Number of pages8
JournalJournal of Heart Valve Disease
Issue number4
Publication statusPublished - Jul 2012


ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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