Understanding Complexity of Cancer Genomes: Lessons from Errors

Sara Martin; Stefano Santaguida

doi:10.1016/j.devcel.2020.05.004

Understanding Complexity of Cancer Genomes: Lessons from Errors

Sara Martin, Stefano Santaguida

Istituto Europeo di Oncologia

Research output: Contribution to journal › Article › peer-review

Abstract

Deconstructing the events leading to cancer genome rearrangements is key to understanding tumorigenesis. In a recent issue of Science, Umbreit, Zhang et al. elegantly show that complex genome evolution is the result of a cascade of events initiated by a single error during cell division.

Original language	English
Pages (from-to)	500-502
Number of pages	3
Journal	Developmental Cell
Volume	53
Issue number	5
DOIs	https://doi.org/10.1016/j.devcel.2020.05.004
Publication status	Published - Jun 8 2020

ASJC Scopus subject areas

Molecular Biology
Biochemistry, Genetics and Molecular Biology(all)
Developmental Biology
Cell Biology

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title = "Understanding Complexity of Cancer Genomes: Lessons from Errors",

abstract = "Deconstructing the events leading to cancer genome rearrangements is key to understanding tumorigenesis. In a recent issue of Science, Umbreit, Zhang et al. elegantly show that complex genome evolution is the result of a cascade of events initiated by a single error during cell division.",

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