Deconstructing the events leading to cancer genome rearrangements is key to understanding tumorigenesis. In a recent issue of Science, Umbreit, Zhang et al. elegantly show that complex genome evolution is the result of a cascade of events initiated by a single error during cell division.
ASJC Scopus subject areas
- Molecular Biology
- Biochemistry, Genetics and Molecular Biology(all)
- Developmental Biology
- Cell Biology