Unexpected clinical outcome in a patient with liver and brain metastasis from melanoma

Carmen Nuzzo, Massimo Zeuli, Virginia Ferraresi, Mariangela Ciccarese, Domenica Pelligrini, Francesco Cognetti

Research output: Contribution to journalArticle

Abstract

The treatment of disseminated melanoma is inadequate. The most active single agents provide brief objective response in 20% of patients, while the combination chemotherapy improves response rates without any apparent survival benefit. Median overall survival is, in fact, 7-9 months and 5 year survival is approximately 6%. Metastatic melanoma with a localization of the disease in the liver and brain are categorized as M1c and have the worst prognosis. Here we describe the history, treatment and favourable clinical outcome in a young man with liver and resected brain metastases who obtained complete remission for 6 years since chemotherapy with dacarbazine, cisplatin and vinblastine.

Original languageEnglish
Pages (from-to)1429-1431
Number of pages3
JournalAnticancer Research
Volume28
Issue number2 B
Publication statusPublished - Mar 2008

Keywords

  • Long-term survival
  • Melanoma
  • Metastatic disease

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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