Unfaithful association of FCGR2B genetic polymorphisms with susceptibility to SLE

Valerio Napolioni, Alessandra Barucca, Elisabetta Bolli, Antonio Concetti, Franco Maria Venanzi

Research output: Contribution to journalArticlepeer-review

Abstract

Correcting errors and proofreading are crucial in a post-genomic era, when DNA sequences are already part of an effective medical screening and treatments. SNPs genotyping of complex human genes can lead to questionable associations if not properly handled. Here, we report about a spurious (reitered) association between FCGR2B genetic polymorphisms and systemic lupus erythematosus.

Original languageEnglish
Pages (from-to)139-142
Number of pages4
JournalAutoimmunity
Volume42
Issue number2
DOIs
Publication statusPublished - 2009

Keywords

  • FCGR2B
  • FCGR2C
  • Homology
  • Single nucleotide polymorphisms
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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