Unifocal stricture of the common bile duct in two children: A localized form of primary sclerosing cholangitis

Etienne M. Sokal, Jean de Ville de Goyet, Jean Paul Buts, Sophie Habets, Serge Gosseye, Philippe Clapuyt, Dominique Claus, Jean Bernard Otte

Research output: Contribution to journalArticle

Abstract

A 4-year-old boy and a 14-year-old girl referred for a cholestatic syndrome were found to have a unifocal stricture of the extrahepatic bile duet. Both radiological (endoscopic-retrograde-choledocopancreatography) and histological findings were suggestive of primary sclerosing cholangitis. There was no past history of chronic inflammatory bowel disease nor any other disorder. Serum autoimmune markers were negative. Complete remission was observed after surgical drainage, and both patients remained symptom-free after a follow-up of 12 months and 8 years, respectively. Such unifocal form of the disease may have a better prognosis than the plurifocal disease. The absence of associated disorders and autoimmunity may also be an indicator of better prognosis in these patients.

Original languageEnglish
Pages (from-to)268-274
Number of pages7
JournalJournal of Pediatric Gastroenterology and Nutrition
Volume11
Issue number2
Publication statusPublished - 1990

Keywords

  • Common bile duct
  • Primary sclerosing cholangitis
  • Unifocal stricture

ASJC Scopus subject areas

  • Gastroenterology
  • Pediatrics, Perinatology, and Child Health
  • Histology
  • Medicine (miscellaneous)
  • Food Science

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