Unilateral amblyopia: An optical coherence tomography study

Anna Dickmann, Sergio Petroni, Annabella Salerni, Roberto Dell'Omo, Emilio Balestrazzi

Research output: Contribution to journalArticle

51 Citations (Scopus)

Abstract

Purpose: To determine whether retinal nerve fiber layer thickness (RNFLT), macular thickness (MT), and foveal volume (FV) in patients with unilateral amblyopia differ between the amblyopic and the sound eye. Methods: A Humphrey-Zeiss Stratus (OCT3) with software 4.0.3.1 was used to evaluate 40 patients (17 male, 23 female; mean age, 15.2 years; range, 5-56 years) with unilateral amblyopia. Patients were divided into 2 groups: 20 strabismic and 20 anisometropic. Maps of macular thickness and RNFL thickness (3.46) created by the use of optical coherence tomography were applied to calculate FV and MT and RNFLT. Results: Mean best-corrected visual acuity was +0.3 LogMAR (range, +0.2 to +1.0) in the amblyopic eye. Mean RNFL thickness was not significantly different between eyes in either group. In strabismic amblyopia, mean MT and FV were 5% lower in the sound eye than in the amblyopic eye (MT, 267 μm vs 253 μm, p = 0.005; FV, 2.57 mm 3 vs 2.43 mm 3, p = 0.001). In anisometropic amblyopia, there was no significant difference between eyes in either MT or FV. Conclusions: In patients with strabismic amblyopia, the MT and FV were slightly but significantly lower in the sound eye than in the amblyopic eye. The clinical importance of this difference is not known. No such difference was observed in patients with anisometropic amblyopia.

Original languageEnglish
Pages (from-to)148-150
Number of pages3
JournalJournal of AAPOS
Volume13
Issue number2
DOIs
Publication statusPublished - Apr 2009

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Amblyopia
Optical Coherence Tomography
Nerve Fibers
Visual Acuity
Software

ASJC Scopus subject areas

  • Ophthalmology
  • Pediatrics, Perinatology, and Child Health

Cite this

Dickmann, A., Petroni, S., Salerni, A., Dell'Omo, R., & Balestrazzi, E. (2009). Unilateral amblyopia: An optical coherence tomography study. Journal of AAPOS, 13(2), 148-150. https://doi.org/10.1016/j.jaapos.2008.10.009

Unilateral amblyopia : An optical coherence tomography study. / Dickmann, Anna; Petroni, Sergio; Salerni, Annabella; Dell'Omo, Roberto; Balestrazzi, Emilio.

In: Journal of AAPOS, Vol. 13, No. 2, 04.2009, p. 148-150.

Research output: Contribution to journalArticle

Dickmann, A, Petroni, S, Salerni, A, Dell'Omo, R & Balestrazzi, E 2009, 'Unilateral amblyopia: An optical coherence tomography study', Journal of AAPOS, vol. 13, no. 2, pp. 148-150. https://doi.org/10.1016/j.jaapos.2008.10.009
Dickmann, Anna ; Petroni, Sergio ; Salerni, Annabella ; Dell'Omo, Roberto ; Balestrazzi, Emilio. / Unilateral amblyopia : An optical coherence tomography study. In: Journal of AAPOS. 2009 ; Vol. 13, No. 2. pp. 148-150.
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