Unilateral nephrectomy and progression of renal failure*

G. Buccianti, M. Lorenz, D. Cresseri, M. L. Bianchi, G. Valenti, F. Cicchetti, B. M. Francucci

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Extensive ablation of renal mass in experimental animals leads to progressive glomerulosclerosis and chronic renal failure (CRF). Clinical studies are far from answering the question whether patients with reduced renal mass are at risk of developing progressive CRF. The aim of our study was to examine the morphological and functional aspects of the remnant kidney in a group of patients who underwent unilateral nephrectomy for renal tuberculosis: 313 patients (161 M, 152 F) mean age 57.2 ± 10.7, were examined after a period ranging from 13.56 to 591.2 months. All patients were on ad libitum diet. Hypertension was found in 34.19% of the patients; SBP was 155.29 ± 19.9 mm Hg and DBP was 92.74 ± 13.07 mm Hg. Estimation of renal size performed by ultrasound scanner gave the following results: length 116.78 ± 8.99 mm; width 58.24 ± 7.21 mm; thickness 17.88 ± 1.96 mm. Kidney function assessed by serum creatinine levels showed a mean level of 1.28 ± 0.53 mg% Forty-two patients (13.41% had serum levels >1.5 mg% but 18 of them had nonconcomitant systemic or renal involvement. Microalbuminuria determined by RIA assay was found in 50.5% of the patients. In our group of patients renal functional impairment was low and hyperfiltration expressed as microalbuminuria does not appear to be a primary factor in the progression of renal failure.

Original languageEnglish
Pages (from-to)415-420
Number of pages6
JournalRenal Failure
Volume15
Issue number3
DOIs
Publication statusPublished - 1993

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Nephrectomy
Renal Insufficiency
Kidney
Chronic Kidney Failure
Renal Tuberculosis
Serum
Creatinine
Diet
Hypertension

Keywords

  • Microalbuminuria
  • Progression of renal failure
  • Renal tuberculosis
  • Unilateral nephrectomy

ASJC Scopus subject areas

  • Nephrology
  • Critical Care and Intensive Care Medicine

Cite this

Buccianti, G., Lorenz, M., Cresseri, D., Bianchi, M. L., Valenti, G., Cicchetti, F., & Francucci, B. M. (1993). Unilateral nephrectomy and progression of renal failure*. Renal Failure, 15(3), 415-420. https://doi.org/10.3109/08860229309054954

Unilateral nephrectomy and progression of renal failure*. / Buccianti, G.; Lorenz, M.; Cresseri, D.; Bianchi, M. L.; Valenti, G.; Cicchetti, F.; Francucci, B. M.

In: Renal Failure, Vol. 15, No. 3, 1993, p. 415-420.

Research output: Contribution to journalArticle

Buccianti, G, Lorenz, M, Cresseri, D, Bianchi, ML, Valenti, G, Cicchetti, F & Francucci, BM 1993, 'Unilateral nephrectomy and progression of renal failure*', Renal Failure, vol. 15, no. 3, pp. 415-420. https://doi.org/10.3109/08860229309054954
Buccianti G, Lorenz M, Cresseri D, Bianchi ML, Valenti G, Cicchetti F et al. Unilateral nephrectomy and progression of renal failure*. Renal Failure. 1993;15(3):415-420. https://doi.org/10.3109/08860229309054954
Buccianti, G. ; Lorenz, M. ; Cresseri, D. ; Bianchi, M. L. ; Valenti, G. ; Cicchetti, F. ; Francucci, B. M. / Unilateral nephrectomy and progression of renal failure*. In: Renal Failure. 1993 ; Vol. 15, No. 3. pp. 415-420.
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