Unilateral ovariectomy-induced luteinizing hormone-releasing hormone content changes in the two halves of the mediobasal hypothalamus

Ida Gerendai, William Rotsztejn, Bianca Marchetti, Claude Kordon, Umberto Scapagnini

Research output: Contribution to journalArticle

Abstract

The luteinizing hormone-releasing hormone (LHRH) content of the two halves of the mediobasal hypothalamus (MBH) has been studied two weeks after unilateral or bilateral ovariectomy (OVX) in the rat. In control animals, the LHRH content of the right-side MBH was higher than that of the left side. Right-side OVX induced a significant increase in LHRH content on the right-side MBH while left-side OVX was followed by elevated LHRH content on the left-side MBH. In contrast, bilateral OVX induced a significant decrease on the right-side MBH. The observation that unilateral OVX induced increased LHRH content in the ipsilateral half of the MBH to OVX, supports the view that a neural pathway might connect the ovary and the MBH.

Original languageEnglish
Pages (from-to)333-336
Number of pages4
JournalNeuroscience Letters
Volume9
Issue number4
DOIs
Publication statusPublished - 1978

Fingerprint

Ovariectomy
Gonadotropin-Releasing Hormone
Hypothalamus
Neural Pathways
Ovary

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Unilateral ovariectomy-induced luteinizing hormone-releasing hormone content changes in the two halves of the mediobasal hypothalamus. / Gerendai, Ida; Rotsztejn, William; Marchetti, Bianca; Kordon, Claude; Scapagnini, Umberto.

In: Neuroscience Letters, Vol. 9, No. 4, 1978, p. 333-336.

Research output: Contribution to journalArticle

Gerendai, Ida ; Rotsztejn, William ; Marchetti, Bianca ; Kordon, Claude ; Scapagnini, Umberto. / Unilateral ovariectomy-induced luteinizing hormone-releasing hormone content changes in the two halves of the mediobasal hypothalamus. In: Neuroscience Letters. 1978 ; Vol. 9, No. 4. pp. 333-336.
@article{adf99710cba641a8a56cd9ecf6646008,
title = "Unilateral ovariectomy-induced luteinizing hormone-releasing hormone content changes in the two halves of the mediobasal hypothalamus",
abstract = "The luteinizing hormone-releasing hormone (LHRH) content of the two halves of the mediobasal hypothalamus (MBH) has been studied two weeks after unilateral or bilateral ovariectomy (OVX) in the rat. In control animals, the LHRH content of the right-side MBH was higher than that of the left side. Right-side OVX induced a significant increase in LHRH content on the right-side MBH while left-side OVX was followed by elevated LHRH content on the left-side MBH. In contrast, bilateral OVX induced a significant decrease on the right-side MBH. The observation that unilateral OVX induced increased LHRH content in the ipsilateral half of the MBH to OVX, supports the view that a neural pathway might connect the ovary and the MBH.",
author = "Ida Gerendai and William Rotsztejn and Bianca Marchetti and Claude Kordon and Umberto Scapagnini",
year = "1978",
doi = "10.1016/0304-3940(78)90204-5",
language = "English",
volume = "9",
pages = "333--336",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "4",

}

TY - JOUR

T1 - Unilateral ovariectomy-induced luteinizing hormone-releasing hormone content changes in the two halves of the mediobasal hypothalamus

AU - Gerendai, Ida

AU - Rotsztejn, William

AU - Marchetti, Bianca

AU - Kordon, Claude

AU - Scapagnini, Umberto

PY - 1978

Y1 - 1978

N2 - The luteinizing hormone-releasing hormone (LHRH) content of the two halves of the mediobasal hypothalamus (MBH) has been studied two weeks after unilateral or bilateral ovariectomy (OVX) in the rat. In control animals, the LHRH content of the right-side MBH was higher than that of the left side. Right-side OVX induced a significant increase in LHRH content on the right-side MBH while left-side OVX was followed by elevated LHRH content on the left-side MBH. In contrast, bilateral OVX induced a significant decrease on the right-side MBH. The observation that unilateral OVX induced increased LHRH content in the ipsilateral half of the MBH to OVX, supports the view that a neural pathway might connect the ovary and the MBH.

AB - The luteinizing hormone-releasing hormone (LHRH) content of the two halves of the mediobasal hypothalamus (MBH) has been studied two weeks after unilateral or bilateral ovariectomy (OVX) in the rat. In control animals, the LHRH content of the right-side MBH was higher than that of the left side. Right-side OVX induced a significant increase in LHRH content on the right-side MBH while left-side OVX was followed by elevated LHRH content on the left-side MBH. In contrast, bilateral OVX induced a significant decrease on the right-side MBH. The observation that unilateral OVX induced increased LHRH content in the ipsilateral half of the MBH to OVX, supports the view that a neural pathway might connect the ovary and the MBH.

UR - http://www.scopus.com/inward/record.url?scp=0018169084&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018169084&partnerID=8YFLogxK

U2 - 10.1016/0304-3940(78)90204-5

DO - 10.1016/0304-3940(78)90204-5

M3 - Article

AN - SCOPUS:0018169084

VL - 9

SP - 333

EP - 336

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 4

ER -