University education and cervical artery dissection

for the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP)-Study Group

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background and purpose: We investigated whether university education is more likely in cervical artery dissection (CeAD)-patients than in age- and sex-matched patients with ischemic stroke (IS) due to other causes (non-CeAD-IS-patients). Methods: Patients from the Cervical Artery Dissection and Ischemic Stroke Patients study with documented self-reported profession before onset of IS due to CeAD (n = 715) or non-CeAD causes (n = 631) were analyzed. In the reported profession, the absence or presence of university education was assessed. Professions could be rated as academic or non-academic in 518 CeAD and 456 non-CeAD patients. Clinical outcome at 3 months was defined as excellent if modified Rankin Scale was 0–1. Results: University education was more frequent in CeAD-patients (100 of 518, 19.3%) than in non-CeAD-IS-patients (61 of 456, 13.4%, p = 0.008). CeAD-patients with and without university education differed significantly with regard to smoking (39 vs. 57%, p = 0.001) and excellent outcome (80 vs. 66%, p = 0.004). In logistic regression analysis, university education was associated with excellent outcome in CeAD-patients (OR 2.44, 95% CI 1.37–5.38) independent of other outcome predictors such as age (OR 0.97, 95% CI 0.84–0.99), NIHSS (OR 0.80, 95% CI 0.76–0.84) and local signs (OR 2.77, 95% CI 1.37–5.57). Conclusion: We observed a higher rate of university education in patients with CeAD compared with non-CeAD patients in our study population. University education was associated with favorable outcome in CeAD-patients. The mechanism behind this association remains unclear.

Original languageEnglish
Pages (from-to)1065-1070
Number of pages6
JournalJournal of Neurology
Volume265
Issue number5
DOIs
Publication statusPublished - May 1 2018

Fingerprint

Dissection
Arteries
Education
Stroke
Patient Education
Logistic Models
Smoking
Regression Analysis

Keywords

  • Cervical artery dissection
  • Ischemic stroke
  • Level of education
  • Outcome
  • Socioeconomic status
  • University education
  • Young adults

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

for the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP)-Study Group (2018). University education and cervical artery dissection. Journal of Neurology, 265(5), 1065-1070. https://doi.org/10.1007/s00415-018-8798-7

University education and cervical artery dissection. / for the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP)-Study Group.

In: Journal of Neurology, Vol. 265, No. 5, 01.05.2018, p. 1065-1070.

Research output: Contribution to journalArticle

for the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP)-Study Group 2018, 'University education and cervical artery dissection', Journal of Neurology, vol. 265, no. 5, pp. 1065-1070. https://doi.org/10.1007/s00415-018-8798-7
for the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP)-Study Group. University education and cervical artery dissection. Journal of Neurology. 2018 May 1;265(5):1065-1070. https://doi.org/10.1007/s00415-018-8798-7
for the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP)-Study Group. / University education and cervical artery dissection. In: Journal of Neurology. 2018 ; Vol. 265, No. 5. pp. 1065-1070.
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abstract = "Background and purpose: We investigated whether university education is more likely in cervical artery dissection (CeAD)-patients than in age- and sex-matched patients with ischemic stroke (IS) due to other causes (non-CeAD-IS-patients). Methods: Patients from the Cervical Artery Dissection and Ischemic Stroke Patients study with documented self-reported profession before onset of IS due to CeAD (n = 715) or non-CeAD causes (n = 631) were analyzed. In the reported profession, the absence or presence of university education was assessed. Professions could be rated as academic or non-academic in 518 CeAD and 456 non-CeAD patients. Clinical outcome at 3 months was defined as excellent if modified Rankin Scale was 0–1. Results: University education was more frequent in CeAD-patients (100 of 518, 19.3{\%}) than in non-CeAD-IS-patients (61 of 456, 13.4{\%}, p = 0.008). CeAD-patients with and without university education differed significantly with regard to smoking (39 vs. 57{\%}, p = 0.001) and excellent outcome (80 vs. 66{\%}, p = 0.004). In logistic regression analysis, university education was associated with excellent outcome in CeAD-patients (OR 2.44, 95{\%} CI 1.37–5.38) independent of other outcome predictors such as age (OR 0.97, 95{\%} CI 0.84–0.99), NIHSS (OR 0.80, 95{\%} CI 0.76–0.84) and local signs (OR 2.77, 95{\%} CI 1.37–5.57). Conclusion: We observed a higher rate of university education in patients with CeAD compared with non-CeAD patients in our study population. University education was associated with favorable outcome in CeAD-patients. The mechanism behind this association remains unclear.",
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AU - Grau, Armin

AU - Pezzini, Alessandro

AU - Debette, Stéphanie

AU - Leys, Didier

AU - Caso, Valeria

AU - Thijs, Vincent N.

AU - Bersano, Anna

AU - Touzé, Emmanuel

AU - Tatlisumak, Turgut

AU - Traenka, Christopher

AU - Lyrer, Philippe A.

AU - Engelter, Stefan T.

AU - Metso, Tiina M.

AU - Grond-Ginsbach, Caspar

AU - Kloss, Manja

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N2 - Background and purpose: We investigated whether university education is more likely in cervical artery dissection (CeAD)-patients than in age- and sex-matched patients with ischemic stroke (IS) due to other causes (non-CeAD-IS-patients). Methods: Patients from the Cervical Artery Dissection and Ischemic Stroke Patients study with documented self-reported profession before onset of IS due to CeAD (n = 715) or non-CeAD causes (n = 631) were analyzed. In the reported profession, the absence or presence of university education was assessed. Professions could be rated as academic or non-academic in 518 CeAD and 456 non-CeAD patients. Clinical outcome at 3 months was defined as excellent if modified Rankin Scale was 0–1. Results: University education was more frequent in CeAD-patients (100 of 518, 19.3%) than in non-CeAD-IS-patients (61 of 456, 13.4%, p = 0.008). CeAD-patients with and without university education differed significantly with regard to smoking (39 vs. 57%, p = 0.001) and excellent outcome (80 vs. 66%, p = 0.004). In logistic regression analysis, university education was associated with excellent outcome in CeAD-patients (OR 2.44, 95% CI 1.37–5.38) independent of other outcome predictors such as age (OR 0.97, 95% CI 0.84–0.99), NIHSS (OR 0.80, 95% CI 0.76–0.84) and local signs (OR 2.77, 95% CI 1.37–5.57). Conclusion: We observed a higher rate of university education in patients with CeAD compared with non-CeAD patients in our study population. University education was associated with favorable outcome in CeAD-patients. The mechanism behind this association remains unclear.

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KW - Ischemic stroke

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KW - Socioeconomic status

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