University education and cervical artery dissection

for the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP)-Study Group

Research output: Contribution to journalArticle

Abstract

Background and purpose: We investigated whether university education is more likely in cervical artery dissection (CeAD)-patients than in age- and sex-matched patients with ischemic stroke (IS) due to other causes (non-CeAD-IS-patients). Methods: Patients from the Cervical Artery Dissection and Ischemic Stroke Patients study with documented self-reported profession before onset of IS due to CeAD (n = 715) or non-CeAD causes (n = 631) were analyzed. In the reported profession, the absence or presence of university education was assessed. Professions could be rated as academic or non-academic in 518 CeAD and 456 non-CeAD patients. Clinical outcome at 3 months was defined as excellent if modified Rankin Scale was 0–1. Results: University education was more frequent in CeAD-patients (100 of 518, 19.3%) than in non-CeAD-IS-patients (61 of 456, 13.4%, p = 0.008). CeAD-patients with and without university education differed significantly with regard to smoking (39 vs. 57%, p = 0.001) and excellent outcome (80 vs. 66%, p = 0.004). In logistic regression analysis, university education was associated with excellent outcome in CeAD-patients (OR 2.44, 95% CI 1.37–5.38) independent of other outcome predictors such as age (OR 0.97, 95% CI 0.84–0.99), NIHSS (OR 0.80, 95% CI 0.76–0.84) and local signs (OR 2.77, 95% CI 1.37–5.57). Conclusion: We observed a higher rate of university education in patients with CeAD compared with non-CeAD patients in our study population. University education was associated with favorable outcome in CeAD-patients. The mechanism behind this association remains unclear.

Original languageEnglish
Pages (from-to)1065-1070
Number of pages6
JournalJournal of Neurology
Volume265
Issue number5
DOIs
Publication statusPublished - May 1 2018

Keywords

  • Cervical artery dissection
  • Ischemic stroke
  • Level of education
  • Outcome
  • Socioeconomic status
  • University education
  • Young adults

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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    for the Cervical Artery Dissection and Ischemic Stroke Patients (CADISP)-Study Group (2018). University education and cervical artery dissection. Journal of Neurology, 265(5), 1065-1070. https://doi.org/10.1007/s00415-018-8798-7