Unravelling the risk factors that underlie oral and oropharyngeal surgery in elderly

G Molteni, S Valerini, M Alicandri-Ciufelli, A E Sprio, E Crosetti, G N Berta, L Presutti, G Succo

Research output: Contribution to journalArticle

Abstract

Oral squamous cell carcinoma (OSCC) diagnoses in elderly patients are expected to double in the next 20 years. Current guidelines suggest surgery as a preferred approach, but elderly patients are hardly considered suitable to challenging surgical treatments. Using a multi-centric retrospective analysis, we evaluated the outcomes of 99 patients affected by OSCC and aged at least 70, who underwent to either transoral procedures (TP), open neck resection without (OR) or with reconstruction (ORR). In our cohort, overall survival was significantly hampered by concomitant diseases and postsurgical complications, whose development is driven by the former. Thus, our findings support the growing acceptance that chronological age alone should not be a sufficient contraindication for aggressive surgery in the treatment of OSCC. However, elderly patients affected by OSCC are undoubtedly delicate surgical candidates and accurate selection prior to surgery with curative intent is mandatory.

Original languageEnglish
Pages (from-to)409-416
Number of pages8
JournalActa Otorhinolaryngologica Italica
Volume38
Issue number5
DOIs
Publication statusPublished - Oct 2018

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Oral Surgery
Squamous Cell Carcinoma
Neck
Guidelines
Survival
Therapeutics

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Unravelling the risk factors that underlie oral and oropharyngeal surgery in elderly. / Molteni, G; Valerini, S; Alicandri-Ciufelli, M; Sprio, A E; Crosetti, E; Berta, G N; Presutti, L; Succo, G.

In: Acta Otorhinolaryngologica Italica, Vol. 38, No. 5, 10.2018, p. 409-416.

Research output: Contribution to journalArticle

Molteni, G, Valerini, S, Alicandri-Ciufelli, M, Sprio, AE, Crosetti, E, Berta, GN, Presutti, L & Succo, G 2018, 'Unravelling the risk factors that underlie oral and oropharyngeal surgery in elderly', Acta Otorhinolaryngologica Italica, vol. 38, no. 5, pp. 409-416. https://doi.org/10.14639/0392-100X-1507
Molteni, G ; Valerini, S ; Alicandri-Ciufelli, M ; Sprio, A E ; Crosetti, E ; Berta, G N ; Presutti, L ; Succo, G. / Unravelling the risk factors that underlie oral and oropharyngeal surgery in elderly. In: Acta Otorhinolaryngologica Italica. 2018 ; Vol. 38, No. 5. pp. 409-416.
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