Abstract
Oral squamous cell carcinoma (OSCC) diagnoses in elderly patients are expected to double in the next 20 years. Current guidelines suggest surgery as a preferred approach, but elderly patients are hardly considered suitable to challenging surgical treatments. Using a multi-centric retrospective analysis, we evaluated the outcomes of 99 patients affected by OSCC and aged at least 70, who underwent to either transoral procedures (TP), open neck resection without (OR) or with reconstruction (ORR). In our cohort, overall survival was significantly hampered by concomitant diseases and postsurgical complications, whose development is driven by the former. Thus, our findings support the growing acceptance that chronological age alone should not be a sufficient contraindication for aggressive surgery in the treatment of OSCC. However, elderly patients affected by OSCC are undoubtedly delicate surgical candidates and accurate selection prior to surgery with curative intent is mandatory.
| Original language | English |
|---|---|
| Pages (from-to) | 409-416 |
| Number of pages | 8 |
| Journal | Acta Otorhinolaryngologica Italica |
| Volume | 38 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - Oct 2018 |
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Unravelling the risk factors that underlie oral and oropharyngeal surgery in elderly. / Molteni, G; Valerini, S; Alicandri-Ciufelli, M; Sprio, A E; Crosetti, E; Berta, G N; Presutti, L; Succo, G.
In: Acta Otorhinolaryngologica Italica, Vol. 38, No. 5, 10.2018, p. 409-416.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Unravelling the risk factors that underlie oral and oropharyngeal surgery in elderly
AU - Molteni, G
AU - Valerini, S
AU - Alicandri-Ciufelli, M
AU - Sprio, A E
AU - Crosetti, E
AU - Berta, G N
AU - Presutti, L
AU - Succo, G
N1 - Copyright © 2018 Società Italiana di Otorinolaringologia e Chirurgia Cervico-Facciale, Rome, Italy.
PY - 2018/10
Y1 - 2018/10
N2 - Oral squamous cell carcinoma (OSCC) diagnoses in elderly patients are expected to double in the next 20 years. Current guidelines suggest surgery as a preferred approach, but elderly patients are hardly considered suitable to challenging surgical treatments. Using a multi-centric retrospective analysis, we evaluated the outcomes of 99 patients affected by OSCC and aged at least 70, who underwent to either transoral procedures (TP), open neck resection without (OR) or with reconstruction (ORR). In our cohort, overall survival was significantly hampered by concomitant diseases and postsurgical complications, whose development is driven by the former. Thus, our findings support the growing acceptance that chronological age alone should not be a sufficient contraindication for aggressive surgery in the treatment of OSCC. However, elderly patients affected by OSCC are undoubtedly delicate surgical candidates and accurate selection prior to surgery with curative intent is mandatory.
AB - Oral squamous cell carcinoma (OSCC) diagnoses in elderly patients are expected to double in the next 20 years. Current guidelines suggest surgery as a preferred approach, but elderly patients are hardly considered suitable to challenging surgical treatments. Using a multi-centric retrospective analysis, we evaluated the outcomes of 99 patients affected by OSCC and aged at least 70, who underwent to either transoral procedures (TP), open neck resection without (OR) or with reconstruction (ORR). In our cohort, overall survival was significantly hampered by concomitant diseases and postsurgical complications, whose development is driven by the former. Thus, our findings support the growing acceptance that chronological age alone should not be a sufficient contraindication for aggressive surgery in the treatment of OSCC. However, elderly patients affected by OSCC are undoubtedly delicate surgical candidates and accurate selection prior to surgery with curative intent is mandatory.
U2 - 10.14639/0392-100X-1507
DO - 10.14639/0392-100X-1507
M3 - Article
C2 - 29393927
VL - 38
SP - 409
EP - 416
JO - Acta Otorhinolaryngologica Italica
JF - Acta Otorhinolaryngologica Italica
SN - 0392-100X
IS - 5
ER -