TY - JOUR
T1 - Unresectable multifocal omental and peritoneal inflammatory myofibroblastic tumor in a child
T2 - Revisiting the role of adjuvant therapy
AU - Bertocchini, Arianna
AU - Lo Zupone, Cristina
AU - Callea, Francesco
AU - Gennari, Fabrizio
AU - Serra, Annalisa
AU - Monti, Lidia
AU - De Ville De Goyet, Jean
PY - 2011/4
Y1 - 2011/4
N2 - Inflammatory myofibroblastic tumor is an uncommon lesion, also called pseudotumor, with a variable natural course from benign with spontaneous regression to mimicking malignant tumors. We report a case of diffuse peritoneal and omental pseudotumor in a 10-year-old boy characterized by aggressive behavior at the onset followed by stability after subtotal resection and chemotherapy. Total excision was not possible because of the tumor dissemination over the whole peritoneal surface. Adjuvant antiinflammatory drug (ketorolac tromethamine) and chemotherapy (methotrexate-vinblastine followed by ifosfamide-adriamycin and ifosfamide alone) were helpful to obtain rapidly complete resolution of clinical symptoms and anatomic stability of the residual lesions. Long-term evolution, in the absence of continued therapy, has been characterized by progressive involution and reduction of the residual masses.
AB - Inflammatory myofibroblastic tumor is an uncommon lesion, also called pseudotumor, with a variable natural course from benign with spontaneous regression to mimicking malignant tumors. We report a case of diffuse peritoneal and omental pseudotumor in a 10-year-old boy characterized by aggressive behavior at the onset followed by stability after subtotal resection and chemotherapy. Total excision was not possible because of the tumor dissemination over the whole peritoneal surface. Adjuvant antiinflammatory drug (ketorolac tromethamine) and chemotherapy (methotrexate-vinblastine followed by ifosfamide-adriamycin and ifosfamide alone) were helpful to obtain rapidly complete resolution of clinical symptoms and anatomic stability of the residual lesions. Long-term evolution, in the absence of continued therapy, has been characterized by progressive involution and reduction of the residual masses.
KW - Chemotherapy
KW - Inflammatory myofibroblastic tumor
KW - Omental tumor
KW - Pediatric
KW - Pseudotumor
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U2 - 10.1016/j.jpedsurg.2011.01.007
DO - 10.1016/j.jpedsurg.2011.01.007
M3 - Article
C2 - 21496520
AN - SCOPUS:79954530570
VL - 46
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
SN - 0022-3468
IS - 4
ER -