Unresectable multifocal omental and peritoneal inflammatory myofibroblastic tumor in a child: Revisiting the role of adjuvant therapy

Arianna Bertocchini, Cristina Lo Zupone, Francesco Callea, Fabrizio Gennari, Annalisa Serra, Lidia Monti, Jean De Ville De Goyet

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Inflammatory myofibroblastic tumor is an uncommon lesion, also called pseudotumor, with a variable natural course from benign with spontaneous regression to mimicking malignant tumors. We report a case of diffuse peritoneal and omental pseudotumor in a 10-year-old boy characterized by aggressive behavior at the onset followed by stability after subtotal resection and chemotherapy. Total excision was not possible because of the tumor dissemination over the whole peritoneal surface. Adjuvant antiinflammatory drug (ketorolac tromethamine) and chemotherapy (methotrexate-vinblastine followed by ifosfamide-adriamycin and ifosfamide alone) were helpful to obtain rapidly complete resolution of clinical symptoms and anatomic stability of the residual lesions. Long-term evolution, in the absence of continued therapy, has been characterized by progressive involution and reduction of the residual masses.

Original languageEnglish
JournalJournal of Pediatric Surgery
Issue number4
Publication statusPublished - Apr 2011



  • Chemotherapy
  • Inflammatory myofibroblastic tumor
  • Omental tumor
  • Pediatric
  • Pseudotumor

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health

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