Abstract
Specialised clinics for the long-term follow-up of survivors from childhood cancer have developed over recent years. The problems encountered among patients who received multiple chemotherapy and radiotherapy can be challenging and require high expertise and close collaboration among different professionals (e.g. oncologists, endocrinologists, radiotherapists, psychologists). Endocrine disorders are often seen, particularly among those who received cranial radiotherapy or gonadotoxic chemotherapy; puberty can be affected and the spectrum of disorders may range from precocious or accelerated puberty to delayed, arrested or even absent pubertal development. Growth impairment can be multifactorial and growth hormone deficiency is an important but probably not the only factor involved. Many questions remain about the optimal management of this group of young patients. In the consensus guidelines that follow the overview an attempt is made to help optimise patients' growth and puberty by suggesting practical clinical approaches to some of the most challenging issues.
| Original language | English |
|---|---|
| Pages (from-to) | 997-1002 |
| Number of pages | 6 |
| Journal | Journal of Pediatric Endocrinology and Metabolism |
| Volume | 14 |
| Issue number | SUPPL. 2 |
| Publication status | Published - 2001 |
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Keywords
- Bone-marrow transplanted patients
- Consensus guidelines
- Growth hormone treatment
- Oncological patients
- Puberty
- Total body irradiation
ASJC Scopus subject areas
- Endocrinology
- Pediatrics, Perinatology, and Child Health
Cite this
Unresolved problems in optimal therapy of pubertal disorders in oncological and bone marrow transplanted patients. / Bozzola, M.; Albanese, A.; Butler, G. E.; Cherubini, V.; Cicognani, A.; Caruso-Nicoletti, M.; Crowne, E.; De Sanctis, V.; Di Battista, E.; Hokken-Koelega, A. C S; Severi, F.; Wonke, B.; Cavallo, L.
In: Journal of Pediatric Endocrinology and Metabolism, Vol. 14, No. SUPPL. 2, 2001, p. 997-1002.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Unresolved problems in optimal therapy of pubertal disorders in oncological and bone marrow transplanted patients
AU - Bozzola, M.
AU - Albanese, A.
AU - Butler, G. E.
AU - Cherubini, V.
AU - Cicognani, A.
AU - Caruso-Nicoletti, M.
AU - Crowne, E.
AU - De Sanctis, V.
AU - Di Battista, E.
AU - Hokken-Koelega, A. C S
AU - Severi, F.
AU - Wonke, B.
AU - Cavallo, L.
PY - 2001
Y1 - 2001
N2 - Specialised clinics for the long-term follow-up of survivors from childhood cancer have developed over recent years. The problems encountered among patients who received multiple chemotherapy and radiotherapy can be challenging and require high expertise and close collaboration among different professionals (e.g. oncologists, endocrinologists, radiotherapists, psychologists). Endocrine disorders are often seen, particularly among those who received cranial radiotherapy or gonadotoxic chemotherapy; puberty can be affected and the spectrum of disorders may range from precocious or accelerated puberty to delayed, arrested or even absent pubertal development. Growth impairment can be multifactorial and growth hormone deficiency is an important but probably not the only factor involved. Many questions remain about the optimal management of this group of young patients. In the consensus guidelines that follow the overview an attempt is made to help optimise patients' growth and puberty by suggesting practical clinical approaches to some of the most challenging issues.
AB - Specialised clinics for the long-term follow-up of survivors from childhood cancer have developed over recent years. The problems encountered among patients who received multiple chemotherapy and radiotherapy can be challenging and require high expertise and close collaboration among different professionals (e.g. oncologists, endocrinologists, radiotherapists, psychologists). Endocrine disorders are often seen, particularly among those who received cranial radiotherapy or gonadotoxic chemotherapy; puberty can be affected and the spectrum of disorders may range from precocious or accelerated puberty to delayed, arrested or even absent pubertal development. Growth impairment can be multifactorial and growth hormone deficiency is an important but probably not the only factor involved. Many questions remain about the optimal management of this group of young patients. In the consensus guidelines that follow the overview an attempt is made to help optimise patients' growth and puberty by suggesting practical clinical approaches to some of the most challenging issues.
KW - Bone-marrow transplanted patients
KW - Consensus guidelines
KW - Growth hormone treatment
KW - Oncological patients
KW - Puberty
KW - Total body irradiation
UR - http://www.scopus.com/inward/record.url?scp=0034879314&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034879314&partnerID=8YFLogxK
M3 - Article
C2 - 11529406
AN - SCOPUS:0034879314
VL - 14
SP - 997
EP - 1002
JO - Journal of Pediatric Endocrinology and Metabolism
JF - Journal of Pediatric Endocrinology and Metabolism
SN - 0334-018X
IS - SUPPL. 2
ER -