Unusual Cutaneous Histiocytosis Expressing an Intermediate Immunophenotype Between Langerhans' Cells and Dermal Macrophages

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Abstract

Cutaneous histiocytosis was discovered in a 40-year-old man with a slow-growing nodule located on his right arm. Histologic findings showed an epidermotropic infiltrate of histiocytes with folded, irregular nuclei. Immunologically, the cells presented an intermediate phenotype between Langerhans' cells and dermal macrophages. After surgical removal of the lesion, neither a relapse nor visceral involvement was observed during two years of follow-up.

Original languageEnglish
Pages (from-to)1250-1253
Number of pages4
JournalArchives of Dermatology
Volume124
Issue number8
DOIs
Publication statusPublished - 1988

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Histiocytosis
Langerhans Cells
Macrophages
Skin
Histiocytes
Phenotype
Recurrence

ASJC Scopus subject areas

  • Dermatology

Cite this

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title = "Unusual Cutaneous Histiocytosis Expressing an Intermediate Immunophenotype Between Langerhans' Cells and Dermal Macrophages",
abstract = "Cutaneous histiocytosis was discovered in a 40-year-old man with a slow-growing nodule located on his right arm. Histologic findings showed an epidermotropic infiltrate of histiocytes with folded, irregular nuclei. Immunologically, the cells presented an intermediate phenotype between Langerhans' cells and dermal macrophages. After surgical removal of the lesion, neither a relapse nor visceral involvement was observed during two years of follow-up.",
author = "Emilio Berti and Raffaele Gianotti and Elvio Alessi",
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