Unusual cytogenetic findings in a synovial sarcoma arising in the paranasal sinuses

Daniela Bettio; Nicoletta Rizzi; Piergiuseppe Colombo; Paolo Bianchi; Paolo Gaetani

doi:10.1016/j.cancergencyto.2004.03.010

Unusual cytogenetic findings in a synovial sarcoma arising in the paranasal sinuses

Daniela Bettio, Nicoletta Rizzi, Piergiuseppe Colombo, Paolo Bianchi, Paolo Gaetani

Research output: Contribution to journal › Article

Abstract

A fresh specimen from an intracranial tumor, which was histopatologically classified as a synovial sarcoma, was investigated cytogenetically. The direct method failed to give any information due to a lack of mitotic cells after treatment with 70% acetic acid, whereas 6-day cultures showed a 45,XY,del(6q),-10 karyotype. The histologic evaluation was consistent with a synovial sarcoma, which is well characterized from a cytogenetic perspective and involves a t(X;18)(p11;q11) in more than 95% of cases. Reverse-transcription polymerase chain reaction analysis did not show the presence of the SYT-SSX chimeric gene.

Original language	English
Pages (from-to)	79-81
Number of pages	3
Journal	Cancer Genetics and Cytogenetics
Volume	155
Issue number	1
DOIs	https://doi.org/10.1016/j.cancergencyto.2004.03.010
Publication status	Published - Nov 2004

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Synovial Sarcoma

Paranasal Sinuses

Cytogenetics

Karyotype

Acetic Acid

Reverse Transcription

Polymerase Chain Reaction

Genes

Neoplasms

ASJC Scopus subject areas

Cancer Research
Genetics
Molecular Biology

Cite this

Bettio, D., Rizzi, N., Colombo, P., Bianchi, P., & Gaetani, P. (2004). Unusual cytogenetic findings in a synovial sarcoma arising in the paranasal sinuses. Cancer Genetics and Cytogenetics, 155(1), 79-81. https://doi.org/10.1016/j.cancergencyto.2004.03.010

Unusual cytogenetic findings in a synovial sarcoma arising in the paranasal sinuses. / Bettio, Daniela; Rizzi, Nicoletta; Colombo, Piergiuseppe ; Bianchi, Paolo; Gaetani, Paolo.

In: Cancer Genetics and Cytogenetics, Vol. 155, No. 1, 11.2004, p. 79-81.

Research output: Contribution to journal › Article

Bettio, D, Rizzi, N, Colombo, P , Bianchi, P & Gaetani, P 2004, 'Unusual cytogenetic findings in a synovial sarcoma arising in the paranasal sinuses', Cancer Genetics and Cytogenetics, vol. 155, no. 1, pp. 79-81. https://doi.org/10.1016/j.cancergencyto.2004.03.010

Bettio D, Rizzi N, Colombo P , Bianchi P, Gaetani P. Unusual cytogenetic findings in a synovial sarcoma arising in the paranasal sinuses. Cancer Genetics and Cytogenetics. 2004 Nov;155(1):79-81. https://doi.org/10.1016/j.cancergencyto.2004.03.010

Bettio, Daniela ; Rizzi, Nicoletta ; Colombo, Piergiuseppe ; Bianchi, Paolo ; Gaetani, Paolo. / Unusual cytogenetic findings in a synovial sarcoma arising in the paranasal sinuses. In: Cancer Genetics and Cytogenetics. 2004 ; Vol. 155, No. 1. pp. 79-81.

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10.1016/j.cancergencyto.2004.03.010