Abstract
The Authors report a case of left adrenal mass incidentally discovered by upper abdominal echogram in a 40 year old man. Physical examination showed no signs of hypercortisolism and plasma cortisol and ACTH levels were in the normal range as well as urinary free cortisol. After adrenalectomy, 4 and 8 month follow-up was performed, without clinical, hormonal and TC evolution. Thirteen months later the patient was referred to our department for widespread oedema, hypertension, hypokalemia and alkalosis. These symptoms were associated with dramatically elevated concentrations of plasmatic and free urinary cortisol. TC showed a large mass in the same adrenal region and diffuse hepatic metastases. In spite of mitotane and ketoconazole therapy the patient died few weeks later.
| Original language | Italian |
|---|---|
| Pages (from-to) | 193-197 |
| Number of pages | 5 |
| Journal | Minerva Endocrinologica |
| Volume | 16 |
| Issue number | 4 |
| Publication status | Published - Oct 1991 |
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ASJC Scopus subject areas
- Medicine(all)
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Insolito comportamento endocrino di carcinoma surrenalico. Studio di un caso. / Zingrillo, M.; Errico, M.; D'Aloiso, L.; Torlontano, M.; Parracino, T.; Gomes, V.
In: Minerva Endocrinologica, Vol. 16, No. 4, 10.1991, p. 193-197.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Insolito comportamento endocrino di carcinoma surrenalico. Studio di un caso.
AU - Zingrillo, M.
AU - Errico, M.
AU - D'Aloiso, L.
AU - Torlontano, M.
AU - Parracino, T.
AU - Gomes, V.
PY - 1991/10
Y1 - 1991/10
N2 - The Authors report a case of left adrenal mass incidentally discovered by upper abdominal echogram in a 40 year old man. Physical examination showed no signs of hypercortisolism and plasma cortisol and ACTH levels were in the normal range as well as urinary free cortisol. After adrenalectomy, 4 and 8 month follow-up was performed, without clinical, hormonal and TC evolution. Thirteen months later the patient was referred to our department for widespread oedema, hypertension, hypokalemia and alkalosis. These symptoms were associated with dramatically elevated concentrations of plasmatic and free urinary cortisol. TC showed a large mass in the same adrenal region and diffuse hepatic metastases. In spite of mitotane and ketoconazole therapy the patient died few weeks later.
AB - The Authors report a case of left adrenal mass incidentally discovered by upper abdominal echogram in a 40 year old man. Physical examination showed no signs of hypercortisolism and plasma cortisol and ACTH levels were in the normal range as well as urinary free cortisol. After adrenalectomy, 4 and 8 month follow-up was performed, without clinical, hormonal and TC evolution. Thirteen months later the patient was referred to our department for widespread oedema, hypertension, hypokalemia and alkalosis. These symptoms were associated with dramatically elevated concentrations of plasmatic and free urinary cortisol. TC showed a large mass in the same adrenal region and diffuse hepatic metastases. In spite of mitotane and ketoconazole therapy the patient died few weeks later.
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M3 - Articolo
C2 - 1815120
AN - SCOPUS:0026235705
VL - 16
SP - 193
EP - 197
JO - Minerva Endocrinologica
JF - Minerva Endocrinologica
SN - 0391-1977
IS - 4
ER -