Unusual features of sebaceous carcinoma in a typical Muir-Torre syndrome

P. Donati, M. C. Ferraro, M. Bellocci, L. M. Muscardin

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A typical Muir-Torre syndrome in two brothers, with different kind of sebaceous tumor in their skin is described. In one of the two brothers an unusual giant primary subcutaneous poorly differentiated sebaceous tumor of the back is observed, until now rarely reported in cutaneous sebaceous tumors in the course of a Muir-Torre syndrome (MTS). The patient is alive and well after a 5-year follow-up, confirming the low malignancy of neoplasms in MTS. The particular histologic features are described, and differential diagnosis with a cutaneous metastasis of visceral tumor is discussed. The implication of the diagnosis of Muir-Torre syndrome reflects a careful study of the patients in order to exclude any visceral neoplasm, including examination of the relatives.

Original languageEnglish
Pages (from-to)383-386
Number of pages4
JournalGiornale Italiano di Dermatologia e Venereologia
Issue number3
Publication statusPublished - 2000


  • Muir-Torre syndrome
  • Sebaceous glands neoplasms
  • Skin neoplasms

ASJC Scopus subject areas

  • Dermatology


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