Unusual manifestations of disseminated neoplasia at presentation: Right-sided heart failure due to a massive cardiac metastasis and autoimmune thrombocytopenia in pleomorphic rhabdomyosarcoma of the adult

Alessandra Semino, Marco Danova, Stefano Perlini, Giovanni Palladini, Alberto Riccardi, Vittorio Perfetti

Research output: Contribution to journalArticlepeer-review

Abstract

Although it is recognized that aggressive soft tissue sarcomas may give rise to cardiac metastases, these manifestations are usually late and clinically silent, being the prevailing finding in exceptional cases. This report describes the occurrence of a massive cardiac metastasis at diagnosis of leg rhabdomyosarcoma in a middle-age adult. This manifestation was the cause of rapidly progressive congestive heart failure and, together with the unusual occurrence of autoimmune thrombocytopenia, led to difficult patient care with a significantly negative influence on the outcome.

Original languageEnglish
Pages (from-to)102-103
Number of pages2
JournalAmerican Journal of Clinical Oncology: Cancer Clinical Trials
Volume29
Issue number1
DOIs
Publication statusPublished - Feb 2006

Keywords

  • Autoimmune thrombocytopenia
  • Cardiac metastasis
  • Heart failure
  • Pleomorphic rhabdomyosarcoma

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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