Unusual manifestations of infections due to Mycoplasma pneumoniae in children

Anna Timitilli, Maya Di Rocco, Giovanni Nattero, Angela Tacchella, Raffaella Giacchino

Research output: Contribution to journalArticlepeer-review


Mycoplasma pneumoniae (Mp) is an important cause of pneumonia in paediatric age, but also other organs or systems can be affected even without pulmonary involvement. The purpose of this study is to stress the unusual clinical features of Mp infection in children. A review of children affected with Mp infection with peculiar pulmonary and/or extra-pulmonary forms is reported. Diagnosis of Mp infection was always confirmed by serum anti-Mp antibody assay. Two patients with infection of the lower airways showed severe respiratory distress; nine cases with only extra-pulmonary manifestations presented urticaria and arthralgia; three patients had severe neuromuscular impairment, one of these resulting in flaccid tetraparesis; one 2-year-old child had anicteric hepatitis, without any sequelae; one case of a 6-year-old child presented severe haemolytic anaemia, and a 5-year-old child with Schönlein-Henoch purpura. In conclusion, Mp infection, a frequent cause of pneumonia at all paediatric ages, may also give rise to extrapulmonary manifestations. Frequently, muscular-articular or neurological systems, skin or other organs are involved. Clinical suspicion of Mp infection is essential in severe cases and the outcome of all pulmonary and/or extra-pulmonary manifestations depends on early diagnosis and specific therapy.

Original languageEnglish
Pages (from-to)113-117
Number of pages5
JournalInfezioni in Medicina
Issue number2
Publication statusPublished - Jun 2004


  • Childhood
  • Extrapulmonary manifestations
  • Mycoplasma pneumoniae

ASJC Scopus subject areas

  • Microbiology (medical)


Dive into the research topics of 'Unusual manifestations of infections due to Mycoplasma pneumoniae in children'. Together they form a unique fingerprint.

Cite this