Abstract
Background: Chronic recurrent multifocal osteomyelitis (CRMO) is a rare condition that commonly affects the clavicle and pelvis. Case presentation: We report here a case a 12 years old girl with CRMO arising with recurrent episodes of left supraorbital headache, followed by the appearance of a periorbital dyschromia. Magnetic resonance imaging (MRI) of the skull and orbits revealed an important subacute inflammatory process. Few months after, the child presented a painful swelling of the left clavicle; the histological examination of the related biopsy allowed to establish the diagnosis of CRMO. Conclusion: CRMO presenting as acute headache involving neurocranium is rare; to our knowledge this is the first recognized case in the world literature. This pathological condition is frequently misdiagnosed as infection or neoplasm and needs a deep investigation for the differential diagnosis. The physical, laboratoristic and instrumental diagnostic investigations of the patient and the treatment employed are described in detail.
Original language | English |
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Article number | 60 |
Journal | Pediatric Rheumatology |
Volume | 13 |
Issue number | 1 |
DOIs | |
Publication status | Published - Dec 12 2015 |
Keywords
- Acute painful headache
- Chronic recurrent multifocal osteomyelitis
- CRMO
ASJC Scopus subject areas
- Rheumatology
- Immunology and Allergy
- Pediatrics, Perinatology, and Child Health