Unusual onset of venous thromboembolism and heparin-induced thrombocytopenia in a patient with essential thrombocythemia

Mario Lapecorella, Alessandro Lucchesi, Mauro Di Ianni, Mariasanta Napolitano, Gino Coletti, Gabriella Di Leonardo, Luigi Dell'Orso, Remo Barnabei, Guglielmo Mariani

Research output: Contribution to journalArticle

Abstract

Essential thrombocythemia is a hematological disorder characterized by clonal hemopoiesis in the bone marrow and increased number of circulating platelets. It is usually discovered accidentally at the time of routine blood examinations or can become clinically evident with either thrombotic or hemorrhagic complications. In the present article, we describe the case of a 66-year-old woman with pneumonia due to Pneumocystis carinii, who experienced deep vein thrombosis and pulmonary embolism during hospitalization with a subsequent heparin-induced thrombocytopenia. Bone marrow examination performed after clinical improvement revealed the patient to be affected by essential thrombocythemia.

Original languageEnglish
Pages (from-to)85-90
Number of pages6
JournalBlood Coagulation and Fibrinolysis
Volume21
Issue number1
DOIs
Publication statusPublished - Jan 2010

Keywords

  • Essential thrombocythemia
  • Heparin-induced thrombocytopenia
  • Pneumocystis carinii
  • Venous thromboembolism

ASJC Scopus subject areas

  • Hematology

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    Lapecorella, M., Lucchesi, A., Di Ianni, M., Napolitano, M., Coletti, G., Di Leonardo, G., Dell'Orso, L., Barnabei, R., & Mariani, G. (2010). Unusual onset of venous thromboembolism and heparin-induced thrombocytopenia in a patient with essential thrombocythemia. Blood Coagulation and Fibrinolysis, 21(1), 85-90. https://doi.org/10.1097/MBC.0b013e32832f2b08