Unusual peptides containing the 2,6-diaminopimelic acid framework: Stereocontrolled synthesis, X-ray analysis, and computational modelling. Part 2

R. Galeazzi, M. Garavelli, A. Grandi, M. Monari, G. Porzi, S. Sandri

Research output: Contribution to journalArticlepeer-review

Abstract

The stereocontrolled synthesis of peptides 6, 9 and 14, structural variants of 2,6-diaminopimelic acid, was carried out starting from the chiral synthon 1, easily obtained from L-valine. The configuration of the introduced stereogenic centres has been assigned on the basis of 1H NMR spectroscopic data. X-Ray crystal structure and conformation analysis of 5 are also reported.

Original languageEnglish
Pages (from-to)2639-2649
Number of pages11
JournalTetrahedron: Asymmetry
Volume14
Issue number17
DOIs
Publication statusPublished - Sep 5 2003

ASJC Scopus subject areas

  • Inorganic Chemistry
  • Organic Chemistry
  • Materials Chemistry
  • Drug Discovery

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