Unusual presentation of sarcoid-like reaction on bone marrow level associated with mediastinal lymphadenopathy on 18F-FDG-PET/CT resembling an early recurrence of Hodgkin's Lymphoma

F. Fallanca, M. Picchio, C. Crivellaro, P. Mapelli, A. M. Samanes Gajate, E. Sabattini, L. Gianolli, C. Messa

Research output: Contribution to journalArticlepeer-review

Abstract

18F-FDG-PET/CT is widely employed to evaluate lymphoma patients. False positive results are quite frequent, generally due to active phase of inflammation. We describe an unusual PET/CT presentation of a sarcoid-like reaction (SLR) in a patient monitored for Hodgkin Lymphoma characterized by an intense uptake in lymph nodes and multiple bone foci in a PET/CT study. The final diagnosis was obtained by biopsy. This study draws attention to the fact that multifocal bone marrow uptakes due to a sarcoideal reaction may be a possible cause of false positive results in 18F-FDG-PET/CT studies in oncology patients.

Original languageEnglish
Pages (from-to)207-209
Number of pages3
JournalRevista Espanola de Medicina Nuclear e Imagen Molecular
Volume31
Issue number4
DOIs
Publication statusPublished - Jul 2012

Keywords

  • F-fluorodeoxyglucose
  • False positive
  • Hodgkin's disease
  • Positron emission tomography
  • Sarcoid-like reaction

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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