Unusual presentation of sarcoid-like reaction on bone marrow level associated with mediastinal lymphadenopathy on 18F-FDG-PET/CT resembling an early recurrence of Hodgkin's Lymphoma

F. Fallanca; M. Picchio; C. Crivellaro; P. Mapelli; A. M. Samanes Gajate; E. Sabattini; L. Gianolli; C. Messa

doi:10.1016/j.remn.2012.03.002

Unusual presentation of sarcoid-like reaction on bone marrow level associated with mediastinal lymphadenopathy on 18F-FDG-PET/CT resembling an early recurrence of Hodgkin's Lymphoma

F. Fallanca, M. Picchio, C. Crivellaro, P. Mapelli, A. M. Samanes Gajate, E. Sabattini, L. Gianolli, C. Messa

IRCCS Ospedale San Raffaele

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Abstract

¹⁸F-FDG-PET/CT is widely employed to evaluate lymphoma patients. False positive results are quite frequent, generally due to active phase of inflammation. We describe an unusual PET/CT presentation of a sarcoid-like reaction (SLR) in a patient monitored for Hodgkin Lymphoma characterized by an intense uptake in lymph nodes and multiple bone foci in a PET/CT study. The final diagnosis was obtained by biopsy. This study draws attention to the fact that multifocal bone marrow uptakes due to a sarcoideal reaction may be a possible cause of false positive results in ¹⁸F-FDG-PET/CT studies in oncology patients.

Original language	English
Pages (from-to)	207-209
Number of pages	3
Journal	Revista Espanola de Medicina Nuclear e Imagen Molecular
Volume	31
Issue number	4
DOIs	https://doi.org/10.1016/j.remn.2012.03.002
Publication status	Published - Jul 2012

Keywords

F-fluorodeoxyglucose
False positive
Hodgkin's disease
Positron emission tomography
Sarcoid-like reaction

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1016/j.remn.2012.03.002

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Fallanca, F., Picchio, M., Crivellaro, C., Mapelli, P., Samanes Gajate, A. M., Sabattini, E., Gianolli, L., & Messa, C. (2012). Unusual presentation of sarcoid-like reaction on bone marrow level associated with mediastinal lymphadenopathy on 18F-FDG-PET/CT resembling an early recurrence of Hodgkin's Lymphoma. Revista Espanola de Medicina Nuclear e Imagen Molecular, 31(4), 207-209. https://doi.org/10.1016/j.remn.2012.03.002

Unusual presentation of sarcoid-like reaction on bone marrow level associated with mediastinal lymphadenopathy on 18F-FDG-PET/CT resembling an early recurrence of Hodgkin's Lymphoma. / Fallanca, F.; Picchio, M.; Crivellaro, C.; Mapelli, P.; Samanes Gajate, A. M.; Sabattini, E.; Gianolli, L.; Messa, C.

In: Revista Espanola de Medicina Nuclear e Imagen Molecular, Vol. 31, No. 4, 07.2012, p. 207-209.

Research output: Contribution to journal › Article › peer-review

Fallanca, F , Picchio, M, Crivellaro, C, Mapelli, P, Samanes Gajate, AM, Sabattini, E, Gianolli, L & Messa, C 2012, 'Unusual presentation of sarcoid-like reaction on bone marrow level associated with mediastinal lymphadenopathy on 18F-FDG-PET/CT resembling an early recurrence of Hodgkin's Lymphoma', Revista Espanola de Medicina Nuclear e Imagen Molecular, vol. 31, no. 4, pp. 207-209. https://doi.org/10.1016/j.remn.2012.03.002

Fallanca F , Picchio M, Crivellaro C, Mapelli P, Samanes Gajate AM, Sabattini E et al. Unusual presentation of sarcoid-like reaction on bone marrow level associated with mediastinal lymphadenopathy on 18F-FDG-PET/CT resembling an early recurrence of Hodgkin's Lymphoma. Revista Espanola de Medicina Nuclear e Imagen Molecular. 2012 Jul;31(4):207-209. https://doi.org/10.1016/j.remn.2012.03.002

Fallanca, F. ; Picchio, M. ; Crivellaro, C. ; Mapelli, P. ; Samanes Gajate, A. M. ; Sabattini, E. ; Gianolli, L. ; Messa, C. / Unusual presentation of sarcoid-like reaction on bone marrow level associated with mediastinal lymphadenopathy on 18F-FDG-PET/CT resembling an early recurrence of Hodgkin's Lymphoma. In: Revista Espanola de Medicina Nuclear e Imagen Molecular. 2012 ; Vol. 31, No. 4. pp. 207-209.

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title = "Unusual presentation of sarcoid-like reaction on bone marrow level associated with mediastinal lymphadenopathy on 18F-FDG-PET/CT resembling an early recurrence of Hodgkin's Lymphoma",

abstract = " 18F-FDG-PET/CT is widely employed to evaluate lymphoma patients. False positive results are quite frequent, generally due to active phase of inflammation. We describe an unusual PET/CT presentation of a sarcoid-like reaction (SLR) in a patient monitored for Hodgkin Lymphoma characterized by an intense uptake in lymph nodes and multiple bone foci in a PET/CT study. The final diagnosis was obtained by biopsy. This study draws attention to the fact that multifocal bone marrow uptakes due to a sarcoideal reaction may be a possible cause of false positive results in 18F-FDG-PET/CT studies in oncology patients.",

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AU - Picchio, M.

AU - Crivellaro, C.

AU - Mapelli, P.

AU - Samanes Gajate, A. M.

AU - Sabattini, E.

AU - Gianolli, L.

AU - Messa, C.

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AB - 18F-FDG-PET/CT is widely employed to evaluate lymphoma patients. False positive results are quite frequent, generally due to active phase of inflammation. We describe an unusual PET/CT presentation of a sarcoid-like reaction (SLR) in a patient monitored for Hodgkin Lymphoma characterized by an intense uptake in lymph nodes and multiple bone foci in a PET/CT study. The final diagnosis was obtained by biopsy. This study draws attention to the fact that multifocal bone marrow uptakes due to a sarcoideal reaction may be a possible cause of false positive results in 18F-FDG-PET/CT studies in oncology patients.

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Unusual presentation of sarcoid-like reaction on bone marrow level associated with mediastinal lymphadenopathy on 18F-FDG-PET/CT resembling an early recurrence of Hodgkin's Lymphoma

Abstract

Keywords

ASJC Scopus subject areas

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