Unusual radiographic appearance of adamantinoma

Michele Cappuccio, Maurizio Montalti, Giuseppe Bosco, Alessandro Gasbarrini, Stefano Boriani

Research output: Contribution to journalArticle

Abstract

Adamantinoma is a rare tumor with an indolent course that occurs most commonly in the tibia. It is locally aggressive, and local recurrences are described after resection. Pain is the most common symptom. Since the lesion is typically slow growing, the pain can be present for many years before the patient seeks medical attention. Microscopically, adamantinoma consists of islands of epithelial cells in a fibrous stroma. Nuclear atypia is minimal, and mitotic figures are rare. The most common radiographic appearance is that of multiple sharply demarcated radiolucent lesions surrounded by areas of dense, sclerotic bone. This tumor most often affects the tibial diaphysis and produces lytic lesions that can cause fractures. A 31-year-old man presented with a rapidly growing lytic lesion of the distal tibia. On histological examination, many areas of epithelial cells in a fibrous stroma were identified. Diagnosis of adamantinoma was performed. The lesion was treated with en bloc resection and reconstruction with distal tibia allograft and ankle arthrodesis with retrograde nail. At 2-year follow-up, there were no clinical or radiological signs of recurrence of disease.

Original languageEnglish
Pages (from-to)926
Number of pages1
JournalOrthopedics
Volume32
Issue number12
DOIs
Publication statusPublished - Dec 2009

Fingerprint

Adamantinoma
Tibia
Epithelial Cells
Recurrence
Pain
Diaphyses
Arthrodesis
Nails
Ankle
Allografts
Neoplasms
Bone and Bones

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Cappuccio, M., Montalti, M., Bosco, G., Gasbarrini, A., & Boriani, S. (2009). Unusual radiographic appearance of adamantinoma. Orthopedics, 32(12), 926. https://doi.org/10.3928/01477447-20091020-22

Unusual radiographic appearance of adamantinoma. / Cappuccio, Michele; Montalti, Maurizio; Bosco, Giuseppe; Gasbarrini, Alessandro; Boriani, Stefano.

In: Orthopedics, Vol. 32, No. 12, 12.2009, p. 926.

Research output: Contribution to journalArticle

Cappuccio, M, Montalti, M, Bosco, G, Gasbarrini, A & Boriani, S 2009, 'Unusual radiographic appearance of adamantinoma', Orthopedics, vol. 32, no. 12, pp. 926. https://doi.org/10.3928/01477447-20091020-22
Cappuccio, Michele ; Montalti, Maurizio ; Bosco, Giuseppe ; Gasbarrini, Alessandro ; Boriani, Stefano. / Unusual radiographic appearance of adamantinoma. In: Orthopedics. 2009 ; Vol. 32, No. 12. pp. 926.
@article{06af82aaffd24d16a81068f592798f0f,
title = "Unusual radiographic appearance of adamantinoma",
abstract = "Adamantinoma is a rare tumor with an indolent course that occurs most commonly in the tibia. It is locally aggressive, and local recurrences are described after resection. Pain is the most common symptom. Since the lesion is typically slow growing, the pain can be present for many years before the patient seeks medical attention. Microscopically, adamantinoma consists of islands of epithelial cells in a fibrous stroma. Nuclear atypia is minimal, and mitotic figures are rare. The most common radiographic appearance is that of multiple sharply demarcated radiolucent lesions surrounded by areas of dense, sclerotic bone. This tumor most often affects the tibial diaphysis and produces lytic lesions that can cause fractures. A 31-year-old man presented with a rapidly growing lytic lesion of the distal tibia. On histological examination, many areas of epithelial cells in a fibrous stroma were identified. Diagnosis of adamantinoma was performed. The lesion was treated with en bloc resection and reconstruction with distal tibia allograft and ankle arthrodesis with retrograde nail. At 2-year follow-up, there were no clinical or radiological signs of recurrence of disease.",
author = "Michele Cappuccio and Maurizio Montalti and Giuseppe Bosco and Alessandro Gasbarrini and Stefano Boriani",
year = "2009",
month = "12",
doi = "10.3928/01477447-20091020-22",
language = "English",
volume = "32",
pages = "926",
journal = "Orthopedics",
issn = "0147-7447",
publisher = "Slack Incorporated",
number = "12",

}

TY - JOUR

T1 - Unusual radiographic appearance of adamantinoma

AU - Cappuccio, Michele

AU - Montalti, Maurizio

AU - Bosco, Giuseppe

AU - Gasbarrini, Alessandro

AU - Boriani, Stefano

PY - 2009/12

Y1 - 2009/12

N2 - Adamantinoma is a rare tumor with an indolent course that occurs most commonly in the tibia. It is locally aggressive, and local recurrences are described after resection. Pain is the most common symptom. Since the lesion is typically slow growing, the pain can be present for many years before the patient seeks medical attention. Microscopically, adamantinoma consists of islands of epithelial cells in a fibrous stroma. Nuclear atypia is minimal, and mitotic figures are rare. The most common radiographic appearance is that of multiple sharply demarcated radiolucent lesions surrounded by areas of dense, sclerotic bone. This tumor most often affects the tibial diaphysis and produces lytic lesions that can cause fractures. A 31-year-old man presented with a rapidly growing lytic lesion of the distal tibia. On histological examination, many areas of epithelial cells in a fibrous stroma were identified. Diagnosis of adamantinoma was performed. The lesion was treated with en bloc resection and reconstruction with distal tibia allograft and ankle arthrodesis with retrograde nail. At 2-year follow-up, there were no clinical or radiological signs of recurrence of disease.

AB - Adamantinoma is a rare tumor with an indolent course that occurs most commonly in the tibia. It is locally aggressive, and local recurrences are described after resection. Pain is the most common symptom. Since the lesion is typically slow growing, the pain can be present for many years before the patient seeks medical attention. Microscopically, adamantinoma consists of islands of epithelial cells in a fibrous stroma. Nuclear atypia is minimal, and mitotic figures are rare. The most common radiographic appearance is that of multiple sharply demarcated radiolucent lesions surrounded by areas of dense, sclerotic bone. This tumor most often affects the tibial diaphysis and produces lytic lesions that can cause fractures. A 31-year-old man presented with a rapidly growing lytic lesion of the distal tibia. On histological examination, many areas of epithelial cells in a fibrous stroma were identified. Diagnosis of adamantinoma was performed. The lesion was treated with en bloc resection and reconstruction with distal tibia allograft and ankle arthrodesis with retrograde nail. At 2-year follow-up, there were no clinical or radiological signs of recurrence of disease.

UR - http://www.scopus.com/inward/record.url?scp=75149175234&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=75149175234&partnerID=8YFLogxK

U2 - 10.3928/01477447-20091020-22

DO - 10.3928/01477447-20091020-22

M3 - Article

C2 - 19968233

AN - SCOPUS:75149175234

VL - 32

SP - 926

JO - Orthopedics

JF - Orthopedics

SN - 0147-7447

IS - 12

ER -