Abstract
We report a case of haploidentical T-depleted BMT that engrafted durably after a highly immunosuppressive conditioning regimen. DNA polymorphism analysis showed that granulocytes and monocytes were donor type but T and B lymphocytes were host derived. Host tolerance to donor antigens was documented. The patient suffered from serious recurrent CMV infections until split chimaerism shifted to full donor type 2 years post-BMT. Seven years after BMT the patient remains in complete remission.
| Original language | English |
|---|---|
| Pages (from-to) | 465-467 |
| Number of pages | 3 |
| Journal | Bone Marrow Transplantation |
| Volume | 18 |
| Issue number | 2 |
| Publication status | Published - Aug 1996 |
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Keywords
- CMV
- Mismatched T-depleted BMT
- Split chimaerism
ASJC Scopus subject areas
- Hematology
- Transplantation
Cite this
Terenzi, A., Aversa, F., Mencarelli, A., Pelicci, P., Velardi, A., Perruccio, K., Martelli, M. F., & Adelmo, T. (1996). Unusual split chimaerism after mismatched T-depleted BMT. Bone Marrow Transplantation, 18(2), 465-467.