We report a case of haploidentical T-depleted BMT that engrafted durably after a highly immunosuppressive conditioning regimen. DNA polymorphism analysis showed that granulocytes and monocytes were donor type but T and B lymphocytes were host derived. Host tolerance to donor antigens was documented. The patient suffered from serious recurrent CMV infections until split chimaerism shifted to full donor type 2 years post-BMT. Seven years after BMT the patient remains in complete remission.
|Number of pages||3|
|Journal||Bone Marrow Transplantation|
|Publication status||Published - Aug 1996|
- Mismatched T-depleted BMT
- Split chimaerism
ASJC Scopus subject areas