Update on capecitabine alone and in combination regimens in colorectal cancer patients

N. Silvestris; E. Maiello; F. De Vita; S. Cinieri; D. Santini; A. Russo; S. Tommasi; A. Azzariti; G. Numico; S. Pisconti; D. Petriella; V. Lorusso; A. Millaku; G. Colucci

doi:10.1016/S0305-7372(10)70020-7

Update on capecitabine alone and in combination regimens in colorectal cancer patients

N. Silvestris, E. Maiello, F. De Vita, S. Cinieri, D. Santini, A. Russo, S. Tommasi, A. Azzariti, G. Numico, S. Pisconti, D. Petriella, V. Lorusso, A. Millaku, G. Colucci

Research output: Contribution to journal › Article › peer-review

Abstract

Capecitabine is an orally administered fluoropyrimidine carbamate which has been developed as a prodrug of 5-FU with the goal to improve its tolerability and intratumoral drug concentration. The review aims to provide an evidence-based update of clinical trials investigating the clinical efficacy, adverse-event profile, dosage and administration of this drug, alone or in combination with conventional chemotherapeutics and/or new target-oriented drugs, in the management of colorectal cancer patients.

Original language	English
Journal	Cancer Treatment Reviews
Volume	36
Issue number	SUPPL. 3
DOIs	https://doi.org/10.1016/S0305-7372(10)70020-7
Publication status	Published - Nov 2010

Keywords

Adjuvant
Bevacizumab
Capecitabine
Cetuximab
Colorectal carcinoma
Irinotecan
Metastatic
Neoadjuvant
Oxaliplatin
Radiotherapy

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging

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Update on capecitabine alone and in combination regimens in colorectal cancer patients. / Silvestris, N.; Maiello, E.; De Vita, F.; Cinieri, S.; Santini, D.; Russo, A.; Tommasi, S.; Azzariti, A.; Numico, G.; Pisconti, S.; Petriella, D.; Lorusso, V.; Millaku, A.; Colucci, G.

In: Cancer Treatment Reviews, Vol. 36, No. SUPPL. 3, 11.2010.

Research output: Contribution to journal › Article › peer-review

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AU - Russo, A.

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