Aggiornamento in tema di trattamento della COPD

Translated title of the contribution: Updates in the treatment of COPD

S. Zaccaria, C. F. Donner

Research output: Contribution to journalArticlepeer-review


Treatment of chronic obstructive pulmonary disease (COPD) is currently multidisciplinary. Available options include the use of topical anticholinergic drugs, which is now a standard of cure for COPD, obviously along with prevention from environmental factors, chest physiotherapy and traditional respiratory treatment (oxygen, ventilation) when needed. Frequently presenting manifestations outcome is dramatic, appearing in a state of so far apparently normal life; in that case treatment must be complex and aggressive from the beginning, possibly with immediate referral for surgical intervention. Broad and standardized use of topical bronchodilators has modified the standard care for COPD. In particular, anticholinergic drugs, both available (ipratropium) or to come (tiotropium) proved simple to use, efficient and very well tolerated. Anticholinergic drugs have been reported superior to the widely tested beta-agonists. Surgical treatment is more complex. Single lung transplant, bilateral lung transplant and lung volume reduction (both as bullaectomy or as regional emphysema resection) are the available surgical options. Major failure risk arise from unaccurate patients selection, and this is true for lung resetion as well as for lung transplant, although indications to lung trasplant are less strict. Both lung volume reduction and lung transplant currently show encouraging and improving results, thank to advances in anestesia procedures and in post-surgical care protocols, not to mention the increasing experience of surgical Centers.

Translated title of the contributionUpdates in the treatment of COPD
Original languageItalian
Pages (from-to)181-187
Number of pages7
Issue number2
Publication statusPublished - 2001

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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