Updating and inhibition processes in working memory: A comparison between Alzheimer's type dementia and frontal lobe focal damage

Francesca Borgo, Lorena Giovannini, Raffaella Moro, Carlo Semenza, Mauro Arcicasa, Marco Zaramella

Research output: Contribution to journalArticlepeer-review

Abstract

A large debate has recently focused on the componential nature of the working-memory system (Baddeley, 1986), as evidenced by functional-imaging studies and by using more sophisticated experimental paradigms. The present work aims at further disentangling the role and effects of central executive (CE) and of phonological loop (PL). It is suggested that maintaining active verbal information mostly relates to an intact PL, while the inhibition of interfering information preponderantly involves the CE. To distinguish these effects, two groups of brain damaged patients were administered with an updating task. Frontal lobe patients showed major difficulties in inhibiting interfering information, an ability requiring an involvement of the CE component. In contrast, Alzheimer's dementia patients evidenced a relative impairment in maintaining relevant information, requiring the intervention of the PL.

Original languageEnglish
Pages (from-to)197-201
Number of pages5
JournalBrain and Cognition
Volume53
Issue number2
DOIs
Publication statusPublished - Nov 2003

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology

Fingerprint Dive into the research topics of 'Updating and inhibition processes in working memory: A comparison between Alzheimer's type dementia and frontal lobe focal damage'. Together they form a unique fingerprint.

Cite this