Updating and inhibition processes in working memory

A comparison between Alzheimer's type dementia and frontal lobe focal damage

Francesca Borgo, Lorena Giovannini, Raffaella Moro, Carlo Semenza, Mauro Arcicasa, Marco Zaramella

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A large debate has recently focused on the componential nature of the working-memory system (Baddeley, 1986), as evidenced by functional-imaging studies and by using more sophisticated experimental paradigms. The present work aims at further disentangling the role and effects of central executive (CE) and of phonological loop (PL). It is suggested that maintaining active verbal information mostly relates to an intact PL, while the inhibition of interfering information preponderantly involves the CE. To distinguish these effects, two groups of brain damaged patients were administered with an updating task. Frontal lobe patients showed major difficulties in inhibiting interfering information, an ability requiring an involvement of the CE component. In contrast, Alzheimer's dementia patients evidenced a relative impairment in maintaining relevant information, requiring the intervention of the PL.

Original languageEnglish
Pages (from-to)197-201
Number of pages5
JournalBrain and Cognition
Volume53
Issue number2
DOIs
Publication statusPublished - Nov 2003

Fingerprint

Frontal Lobe
Short-Term Memory
Alzheimer Disease
Aptitude
Brain
Inhibition (Psychology)
Damage
Alzheimer
Dementia
Working Memory
Central Executive
Phonological Loop

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology

Cite this

Updating and inhibition processes in working memory : A comparison between Alzheimer's type dementia and frontal lobe focal damage. / Borgo, Francesca; Giovannini, Lorena; Moro, Raffaella; Semenza, Carlo; Arcicasa, Mauro; Zaramella, Marco.

In: Brain and Cognition, Vol. 53, No. 2, 11.2003, p. 197-201.

Research output: Contribution to journalArticle

Borgo, Francesca ; Giovannini, Lorena ; Moro, Raffaella ; Semenza, Carlo ; Arcicasa, Mauro ; Zaramella, Marco. / Updating and inhibition processes in working memory : A comparison between Alzheimer's type dementia and frontal lobe focal damage. In: Brain and Cognition. 2003 ; Vol. 53, No. 2. pp. 197-201.
@article{360ccbb60cff410983b2e0fd565fbd40,
title = "Updating and inhibition processes in working memory: A comparison between Alzheimer's type dementia and frontal lobe focal damage",
abstract = "A large debate has recently focused on the componential nature of the working-memory system (Baddeley, 1986), as evidenced by functional-imaging studies and by using more sophisticated experimental paradigms. The present work aims at further disentangling the role and effects of central executive (CE) and of phonological loop (PL). It is suggested that maintaining active verbal information mostly relates to an intact PL, while the inhibition of interfering information preponderantly involves the CE. To distinguish these effects, two groups of brain damaged patients were administered with an updating task. Frontal lobe patients showed major difficulties in inhibiting interfering information, an ability requiring an involvement of the CE component. In contrast, Alzheimer's dementia patients evidenced a relative impairment in maintaining relevant information, requiring the intervention of the PL.",
author = "Francesca Borgo and Lorena Giovannini and Raffaella Moro and Carlo Semenza and Mauro Arcicasa and Marco Zaramella",
year = "2003",
month = "11",
doi = "10.1016/S0278-2626(03)00109-X",
language = "English",
volume = "53",
pages = "197--201",
journal = "Brain and Cognition",
issn = "0278-2626",
publisher = "Academic Press Inc.",
number = "2",

}

TY - JOUR

T1 - Updating and inhibition processes in working memory

T2 - A comparison between Alzheimer's type dementia and frontal lobe focal damage

AU - Borgo, Francesca

AU - Giovannini, Lorena

AU - Moro, Raffaella

AU - Semenza, Carlo

AU - Arcicasa, Mauro

AU - Zaramella, Marco

PY - 2003/11

Y1 - 2003/11

N2 - A large debate has recently focused on the componential nature of the working-memory system (Baddeley, 1986), as evidenced by functional-imaging studies and by using more sophisticated experimental paradigms. The present work aims at further disentangling the role and effects of central executive (CE) and of phonological loop (PL). It is suggested that maintaining active verbal information mostly relates to an intact PL, while the inhibition of interfering information preponderantly involves the CE. To distinguish these effects, two groups of brain damaged patients were administered with an updating task. Frontal lobe patients showed major difficulties in inhibiting interfering information, an ability requiring an involvement of the CE component. In contrast, Alzheimer's dementia patients evidenced a relative impairment in maintaining relevant information, requiring the intervention of the PL.

AB - A large debate has recently focused on the componential nature of the working-memory system (Baddeley, 1986), as evidenced by functional-imaging studies and by using more sophisticated experimental paradigms. The present work aims at further disentangling the role and effects of central executive (CE) and of phonological loop (PL). It is suggested that maintaining active verbal information mostly relates to an intact PL, while the inhibition of interfering information preponderantly involves the CE. To distinguish these effects, two groups of brain damaged patients were administered with an updating task. Frontal lobe patients showed major difficulties in inhibiting interfering information, an ability requiring an involvement of the CE component. In contrast, Alzheimer's dementia patients evidenced a relative impairment in maintaining relevant information, requiring the intervention of the PL.

UR - http://www.scopus.com/inward/record.url?scp=0242494158&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0242494158&partnerID=8YFLogxK

U2 - 10.1016/S0278-2626(03)00109-X

DO - 10.1016/S0278-2626(03)00109-X

M3 - Article

VL - 53

SP - 197

EP - 201

JO - Brain and Cognition

JF - Brain and Cognition

SN - 0278-2626

IS - 2

ER -