Upper airway involvement in pediatric COVID-19

Giuseppe Fabio Parisi, Giulia Brindisi, Cristiana Indolfi, Lucia Diaferio, Giuseppe Marchese, Daniele G. Ghiglioni, Anna Maria Zicari, Michele Miraglia del Giudice

Research output: Contribution to journalArticlepeer-review


The clinical spectrum of SARS-CoV-2 infection is mixed. It ranges from asymptomatic cases, medium-intensity forms with mild to moderate symptoms, to severe ones with bilateral lung involvement and respiratory distress, which can require transfer to ICUs and intubation. In most cases, the clinical picture is characterized by a persistent fever, cough, dyspnoea, expectoration, myalgias, arthralgias, headache, gastrointestinal symptoms, nasal congestion, and pharyngodynia. The spread of COVID-19 in Europe has highlighted an atypical presentation of disease involving upper airways and, above all, dysfunction of olfactory and gustatory senses. There is ample evidence that COVID-19 is significantly less severe in children than in adults. However, due to difficulties in assessing the disorder in children, especially among very young patients, the olfaction and gustatory dysfunctions remain open issues. This article sheds light on the upper airway involvement in pediatric COVID-19 subjects.

Original languageEnglish
Pages (from-to)85-88
Number of pages4
JournalPediatric Allergy and Immunology
Issue numberS26
Publication statusPublished - Nov 2020


  • ageusia
  • anosmia
  • Children
  • coronavirus
  • COVID-19
  • upper airway

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy
  • Immunology


Dive into the research topics of 'Upper airway involvement in pediatric COVID-19'. Together they form a unique fingerprint.

Cite this