Urgency of micturition and detrusor contractility in men with prostatic obstruction and overactive bladders

Antonio Cucchi, S. Quaglini, A. Giannantoni, C. Guarnaschelli, B. Rovereto

Research output: Contribution to journalArticle

Abstract

Aims: In men with prostatic obstruction and detrusor overactivity (DO), to ascertain whether urgency of micturition affects bladder contractility. Materials and Methods: We urodynamically assessed five groups of 20 men each who had bladder outflow obstruction (BOO) from benign prostatic enlargement-Groups 1 (with no DO and no urgency), 2 (with DO and no urgency), 3A (with DO and moderate urgency), 3B (with DO and severe urgency), and 4 (with DO, severe urgency and chronic ischemic cerebral lesions). Urgency was graded as moderate or severe by the ability to avert an urgent void at cystometry for ≥2 or max. Results: AG did not differ significantly in Groups 2, 3A, and 3B, proved higher in such groups than in Group 1, and was nearly the same in Groups 1 and 4. PIP and WFmax were significantly higher in Groups 2, 3A, and 3B than in Groups 1 and 4, had the highest levels in Group 3B, and did not differ significantly in Groups 1-4 and 2-3A. Conclusions: In DO patients with prostatic obstruction there seems to be a DO-related facilitation of bladder contractility. In the same patients, severe urgency of micturition might over-amplify (i.e., enhance a DO-related facilitation of) bladder contractility, provided there are no neurogenic (chronic ischemic cerebral) lesions.

Original languageEnglish
Pages (from-to)202-206
Number of pages5
JournalNeurourology and Urodynamics
Volume24
Issue number3
DOIs
Publication statusPublished - 2005

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Overactive Urinary Bladder
Urination
Urinary Bladder

Keywords

  • Bladder contractility
  • Bladder outflow obstruction
  • Bladder sensation
  • Detrusor overactivity
  • Urgency

ASJC Scopus subject areas

  • Clinical Neurology
  • Nephrology
  • Urology

Cite this

Urgency of micturition and detrusor contractility in men with prostatic obstruction and overactive bladders. / Cucchi, Antonio; Quaglini, S.; Giannantoni, A.; Guarnaschelli, C.; Rovereto, B.

In: Neurourology and Urodynamics, Vol. 24, No. 3, 2005, p. 202-206.

Research output: Contribution to journalArticle

Cucchi, Antonio ; Quaglini, S. ; Giannantoni, A. ; Guarnaschelli, C. ; Rovereto, B. / Urgency of micturition and detrusor contractility in men with prostatic obstruction and overactive bladders. In: Neurourology and Urodynamics. 2005 ; Vol. 24, No. 3. pp. 202-206.
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AU - Rovereto, B.

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N2 - Aims: In men with prostatic obstruction and detrusor overactivity (DO), to ascertain whether urgency of micturition affects bladder contractility. Materials and Methods: We urodynamically assessed five groups of 20 men each who had bladder outflow obstruction (BOO) from benign prostatic enlargement-Groups 1 (with no DO and no urgency), 2 (with DO and no urgency), 3A (with DO and moderate urgency), 3B (with DO and severe urgency), and 4 (with DO, severe urgency and chronic ischemic cerebral lesions). Urgency was graded as moderate or severe by the ability to avert an urgent void at cystometry for ≥2 or max. Results: AG did not differ significantly in Groups 2, 3A, and 3B, proved higher in such groups than in Group 1, and was nearly the same in Groups 1 and 4. PIP and WFmax were significantly higher in Groups 2, 3A, and 3B than in Groups 1 and 4, had the highest levels in Group 3B, and did not differ significantly in Groups 1-4 and 2-3A. Conclusions: In DO patients with prostatic obstruction there seems to be a DO-related facilitation of bladder contractility. In the same patients, severe urgency of micturition might over-amplify (i.e., enhance a DO-related facilitation of) bladder contractility, provided there are no neurogenic (chronic ischemic cerebral) lesions.

AB - Aims: In men with prostatic obstruction and detrusor overactivity (DO), to ascertain whether urgency of micturition affects bladder contractility. Materials and Methods: We urodynamically assessed five groups of 20 men each who had bladder outflow obstruction (BOO) from benign prostatic enlargement-Groups 1 (with no DO and no urgency), 2 (with DO and no urgency), 3A (with DO and moderate urgency), 3B (with DO and severe urgency), and 4 (with DO, severe urgency and chronic ischemic cerebral lesions). Urgency was graded as moderate or severe by the ability to avert an urgent void at cystometry for ≥2 or max. Results: AG did not differ significantly in Groups 2, 3A, and 3B, proved higher in such groups than in Group 1, and was nearly the same in Groups 1 and 4. PIP and WFmax were significantly higher in Groups 2, 3A, and 3B than in Groups 1 and 4, had the highest levels in Group 3B, and did not differ significantly in Groups 1-4 and 2-3A. Conclusions: In DO patients with prostatic obstruction there seems to be a DO-related facilitation of bladder contractility. In the same patients, severe urgency of micturition might over-amplify (i.e., enhance a DO-related facilitation of) bladder contractility, provided there are no neurogenic (chronic ischemic cerebral) lesions.

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