Uric acid in the early risk stratification of ST-elevation myocardial infarction

Chiara Lazzeri, Serafina Valente, Marco Chiostri, Claudio Picariello, Gian Franco Gensini

Research output: Contribution to journalArticlepeer-review


Controversy still exists about uric acid as a potential prognosticrisk factor for outcomes in patients with acute myocardial infarction. We prospectively assessed, in 856 patients with ST-elevation myocardial infarction (STMI) consecutively admitted to our Intensive Cardiac Care Unit after primary percutaneous coronary intervention (PCI) whether uric acid (UA) levels are associated with in-hospital mortality and complications. Killip classes III--IV were more frequent in the 3° UA tertile that was associated with the highest values of peak Tn I (p = 0.005), NT-proBNP (p 2), uric acid lost its statistical significance, while Tn I (100 pg/ml step OR: 1.002; 95% CI 1.000-1.003; p = 0.007) and renal failure (OR 9.16; 95% CI 3.60-23.32; p

Original languageEnglish
Pages (from-to)33-39
Number of pages7
JournalInternal and Emergency Medicine
Issue number1
Publication statusPublished - Feb 2012


  • Percutaneous coronary intervention
  • Risk stratification
  • ST-elevation myocardial infarction
  • Uric acid

ASJC Scopus subject areas

  • Emergency Medicine
  • Internal Medicine


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