Urinary 17OHCS levels in psoriatic out-patients treated with topical corticosteroids

C. Pelfini, M. Vignini, R. Pericoli, G. Rabbiosi

Research output: Contribution to journalArticlepeer-review


Absorption of topical corticosteroids produces systemic effects detectable by determination of plasma ACTH, cortisol, and its metabolites. As previously reported, the 24-hour urinary hydroxycorticoids (17OHCS) determination is a simple and sensitive index of adrenal suppression. A study of the 17OHCS level in 30 psoriatic out-patients using topical corticosteroids was conducted. Results showed a significant decrease in the 17OHCS levels in patients treated with more than 90 g/week of potent or very potent corticosteroid preparations. A comparison of these findings and our data obtained in psoriatic in-patients treated under supervised conditions is also included.

Original languageEnglish
Pages (from-to)71-74
Number of pages4
JournalActa Dermato-Venereologica
Issue numberSUPPL. 113
Publication statusPublished - 1984

ASJC Scopus subject areas

  • Dermatology


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