Urinary bladder preservation for muscle-invasive bladder cancer: A survey among radiation oncologists of Lombardy, Italy

Barbara Alicja Jereczek-Fossa, Renzo Colombo, Tiziana Magnani, Cristiana Fodor, Marianna Alessandra Gerardi, Paolo Antognoni, Lucia Barsacchi, Nice Bedini, Stefano Bracelli, Alberto Buffoli, Emanuela Cagna, Gianpiero Catalano, Stefania Gottardo, Corrado Italia, Giovanni Battista Ivaldi, Stefano Masciullo, Anna Merlotti, Enrico Sarti, Marta Scorsetti, Flavia SerafiniMariasole Toninelli, Elisabetta Vitali, Riccardo Valdagni, Elisa Villa, Dario Zerini, Ottavio De Cobelli, Roberto Orecchia

Research output: Contribution to journalArticlepeer-review

Abstract

Aims and background: Bladder preservation is a treatment option in muscle-invasive bladder carcinoma. The most investigated approach is a trimodality schedule including maximum transurethral resection of bladder tumor (TURBT) followed by chemoradiotherapy. Our aim was to evaluate the use of bladder preservation by radiation oncologists of the Lombardy region in Italy. Methods and study design: A survey with 13 items regarding data of 2012 was sent to all 32 radiotherapy centers within the collaboration between the Lombardy Oncological Network and the Lombardy Section of the Italian Society of Oncological Radiotherapy. Results: Thirteen centers (41%) answered the survey; the presented data come from 11 active centers. In these centers, 11,748 patients were treated with external-beam radiotherapy in 2012, 100 of whom having bladder cancer (0.9%). 74/100 patients received radiotherapy as palliative treatment for T, N or M lesions. A further 9 and 5 patients received radiotherapy for oligometastatic disease (ablative doses to small volumes) and postoperatively, respectively. Bladder preservation was performed in 12 cases and included trimodality and other strategies (mainly TURBT followed by radiotherapy). A multidisciplinary urology tumor board met regularly in 5 of 11 centers. All responders declared their interest in the Lombardy multicenter collaboration on bladder preservation. Conclusions: Our survey showed that bladder preservation is rarely used in Lombardy despite the availability of the latest radiotherapy technologies and the presence of an urology tumor board in half of the centers. The initiative of multicenter and multidisciplinary collaboration was undertaken to prepare the platform for bladder preservation as a treatment option in selected patients.

Original languageEnglish
Pages (from-to)174-178
Number of pages5
JournalTumori
Volume101
Issue number2
DOIs
Publication statusPublished - Mar 1 2015

Keywords

  • Bladder preservation
  • Muscle-invasive bladder cancer
  • Trimodality approach

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Medicine(all)

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