Urinary colony-stimulating factor in acute leukemia follow-up and correlation with various phases of the disease

G. L. Bianchi Scarra, F. Ajmar, R. Barresi, A. Ferraris, M. Sessarego, M. Fella

Research output: Contribution to journalArticlepeer-review

Abstract

Urinary colony-stimulating factor (CSF) was assayed in 19 patients with various leukemias and was monitored in various phases of acute leukemia in 3 patients. Significantly higher CSF levels were found at the onset of leukemia with a monoblastic component. Continuous monitoring of CSF in a patient with acute myelomonocytic leukemia revealed a decrease in CSF level during the remission phase, followed by a rebound to high levels preceding the clinical and hematological relapse. Concomitantly, a colony-inhibitory factor (CIF) was detected. Both CSF and CIF of this patient were isolated and partially characterized.

Original languageEnglish
Pages (from-to)253-262
Number of pages10
JournalActa Haematologica
Volume65
Issue number4
Publication statusPublished - 1981

ASJC Scopus subject areas

  • Hematology

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