Abstract
Urinary excretion of ethylenethiourea (ETU) was monitored for 8 days in a group of five male non-smoker volunteers on a diet, the items of which were assayed for ETU and carbon sulphide. Urinary excretion of ETU reflected the consumption of wine, fruit and vegetables. Urinary ETU concentrations ranged from 0.6 to 6.7 μg/g creatinine. ETU concentrations in the food eaten by the volunteers were generally below the detection limit whereas in wine 8.8 μg/l ETU was detected. Evolution of carbon sulphide by food samples ranged from 0.03 to 0.17 mg/kg. Mean (± S.D.) daily intake of ETU in wine was 3.5 ± 0.2% of the acceptable daily intake (ADI): 0.070 ± 0.004 μg/kg body wt. During the 8 days of the study, an average of 48.3% of the ETU ingested in wine was excreted unmodified by the kidneys. Twenty-four-hour urinary excretion of ETU was significantly correlated with daily intake of ETU (r = 0.768) and CS2 evolved by the daily food items (r = 0.414).
| Original language | English |
|---|---|
| Pages (from-to) | 167-179 |
| Number of pages | 13 |
| Journal | Science of the Total Environment |
| Volume | 203 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Sep 6 1997 |
Fingerprint
Keywords
- Dietary intake
- Ethylenebisdithiocarbamates
- Ethylenethiourea
- General population
ASJC Scopus subject areas
- Environmental Chemistry
- Environmental Science(all)
Cite this
Urinary excretion of ethylenethiourea in five volunteers on a controlled diet (multicentric study). / Aprea, C.; Betta, A.; Catenacci, G.; Colli, A.; Lotti, A.; Minoia, C.; Olivieri, P.; Passini, V.; Pavan, I.; Roggi, C.; Ruggeri, R.; Sciarra, G.; Turci, R.; Vannini, P.; Vitalone, V.
In: Science of the Total Environment, Vol. 203, No. 2, 06.09.1997, p. 167-179.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Urinary excretion of ethylenethiourea in five volunteers on a controlled diet (multicentric study)
AU - Aprea, C.
AU - Betta, A.
AU - Catenacci, G.
AU - Colli, A.
AU - Lotti, A.
AU - Minoia, C.
AU - Olivieri, P.
AU - Passini, V.
AU - Pavan, I.
AU - Roggi, C.
AU - Ruggeri, R.
AU - Sciarra, G.
AU - Turci, R.
AU - Vannini, P.
AU - Vitalone, V.
PY - 1997/9/6
Y1 - 1997/9/6
N2 - Urinary excretion of ethylenethiourea (ETU) was monitored for 8 days in a group of five male non-smoker volunteers on a diet, the items of which were assayed for ETU and carbon sulphide. Urinary excretion of ETU reflected the consumption of wine, fruit and vegetables. Urinary ETU concentrations ranged from 0.6 to 6.7 μg/g creatinine. ETU concentrations in the food eaten by the volunteers were generally below the detection limit whereas in wine 8.8 μg/l ETU was detected. Evolution of carbon sulphide by food samples ranged from 0.03 to 0.17 mg/kg. Mean (± S.D.) daily intake of ETU in wine was 3.5 ± 0.2% of the acceptable daily intake (ADI): 0.070 ± 0.004 μg/kg body wt. During the 8 days of the study, an average of 48.3% of the ETU ingested in wine was excreted unmodified by the kidneys. Twenty-four-hour urinary excretion of ETU was significantly correlated with daily intake of ETU (r = 0.768) and CS2 evolved by the daily food items (r = 0.414).
AB - Urinary excretion of ethylenethiourea (ETU) was monitored for 8 days in a group of five male non-smoker volunteers on a diet, the items of which were assayed for ETU and carbon sulphide. Urinary excretion of ETU reflected the consumption of wine, fruit and vegetables. Urinary ETU concentrations ranged from 0.6 to 6.7 μg/g creatinine. ETU concentrations in the food eaten by the volunteers were generally below the detection limit whereas in wine 8.8 μg/l ETU was detected. Evolution of carbon sulphide by food samples ranged from 0.03 to 0.17 mg/kg. Mean (± S.D.) daily intake of ETU in wine was 3.5 ± 0.2% of the acceptable daily intake (ADI): 0.070 ± 0.004 μg/kg body wt. During the 8 days of the study, an average of 48.3% of the ETU ingested in wine was excreted unmodified by the kidneys. Twenty-four-hour urinary excretion of ETU was significantly correlated with daily intake of ETU (r = 0.768) and CS2 evolved by the daily food items (r = 0.414).
KW - Dietary intake
KW - Ethylenebisdithiocarbamates
KW - Ethylenethiourea
KW - General population
UR - http://www.scopus.com/inward/record.url?scp=0030739922&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030739922&partnerID=8YFLogxK
U2 - 10.1016/S0048-9697(97)00145-9
DO - 10.1016/S0048-9697(97)00145-9
M3 - Article
C2 - 9281842
AN - SCOPUS:0030739922
VL - 203
SP - 167
EP - 179
JO - Science of the Total Environment
JF - Science of the Total Environment
SN - 0048-9697
IS - 2
ER -