Urotensin-II as an angiogenic factor

Diego Guidolin; Giovanna Albertin; Domenico Ribatti

doi:10.1016/j.peptides.2010.03.022

Urotensin-II as an angiogenic factor

Diego Guidolin, Giovanna Albertin, Domenico Ribatti

IRCCS Giovanni Paolo II

Research output: Contribution to journal › Article › peer-review

Abstract

Angiogenesis, the process through which new blood vessels arise from pre-existing ones, is regulated by numerous "classic" factors and other "nonclassic" regulators of angiogenesis. Among these latter urotensin-II is a cyclic 11-amino acid (human) or 15-amino acid (rodent) peptide, originally isolated from the fish urophysis, which exerts a potent systemic vasoconstrictor and hypertensive effect. This review article summarizes the literature data concerning the involvement of urotensin-II in angiogenesis.

Original language	English
Pages (from-to)	1219-1224
Number of pages	6
Journal	Peptides
Volume	31
Issue number	6
DOIs	https://doi.org/10.1016/j.peptides.2010.03.022
Publication status	Published - Jun 2010

Keywords

Angiogenesis
Antiangiogenesis
Urotensin

ASJC Scopus subject areas

Biochemistry
Endocrinology
Physiology
Cellular and Molecular Neuroscience

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10.1016/j.peptides.2010.03.022

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AB - Angiogenesis, the process through which new blood vessels arise from pre-existing ones, is regulated by numerous "classic" factors and other "nonclassic" regulators of angiogenesis. Among these latter urotensin-II is a cyclic 11-amino acid (human) or 15-amino acid (rodent) peptide, originally isolated from the fish urophysis, which exerts a potent systemic vasoconstrictor and hypertensive effect. This review article summarizes the literature data concerning the involvement of urotensin-II in angiogenesis.

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KW - Antiangiogenesis

KW - Urotensin

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Urotensin-II as an angiogenic factor

Abstract

Keywords

ASJC Scopus subject areas

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