Abstract
Angiogenesis, the process through which new blood vessels arise from pre-existing ones, is regulated by numerous "classic" factors and other "nonclassic" regulators of angiogenesis. Among these latter urotensin-II is a cyclic 11-amino acid (human) or 15-amino acid (rodent) peptide, originally isolated from the fish urophysis, which exerts a potent systemic vasoconstrictor and hypertensive effect. This review article summarizes the literature data concerning the involvement of urotensin-II in angiogenesis.
Original language | English |
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Pages (from-to) | 1219-1224 |
Number of pages | 6 |
Journal | Peptides |
Volume | 31 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 2010 |
Keywords
- Angiogenesis
- Antiangiogenesis
- Urotensin
ASJC Scopus subject areas
- Biochemistry
- Endocrinology
- Physiology
- Cellular and Molecular Neuroscience