Urotensin-II as an angiogenic factor

Diego Guidolin, Giovanna Albertin, Domenico Ribatti

Research output: Contribution to journalArticlepeer-review


Angiogenesis, the process through which new blood vessels arise from pre-existing ones, is regulated by numerous "classic" factors and other "nonclassic" regulators of angiogenesis. Among these latter urotensin-II is a cyclic 11-amino acid (human) or 15-amino acid (rodent) peptide, originally isolated from the fish urophysis, which exerts a potent systemic vasoconstrictor and hypertensive effect. This review article summarizes the literature data concerning the involvement of urotensin-II in angiogenesis.

Original languageEnglish
Pages (from-to)1219-1224
Number of pages6
Issue number6
Publication statusPublished - Jun 2010


  • Angiogenesis
  • Antiangiogenesis
  • Urotensin

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology
  • Physiology
  • Cellular and Molecular Neuroscience


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