Use of a levonorgestrel-releasing intrauterine device in the treatment of rectovaginal endometriosis

Luigi Fedele, Stefano Bianchi, Giovanni Zanconato, Antonella Portuese, Ricciarda Raffaelli

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: To evaluate the effectiveness of a levonorgestrel-releasing IUD as therapy for endometriosis of the rectovaginal septum. Design: Prospective therapeutic non-randomized, self-controlled clinical trial analyzing changes in pain symptoms and size of lesions induced by the levonorgestrel-releasing IUD over 12 months. Setting: Tertiary referral center for treatment of deep endometriosis. Patient(s): Eleven symptomatic patients with rectovaginal endometriosis.Intervention(s): A levonorgestrel-releasing IUD was inserted and maintained for 12 months. Main Outcome Measure(s): Severity of dysmenorrhea, pelvic pain, and deep dyspareunia were assessed before insertion of the IUD and throughout treatment. The size of rectovaginal endometriotic lesions were evaluated by using transrectal and transvaginal ultrasonography. Result(s): Dysmenorrhea, pelvic pain, and deep dyspareunia greatly improved and the size of the endometriotic lesions was significantly reduced by treatment. Conclusion(s): Insertion of a levonorgestrel-releasing IUD alleviates pain and reduces the size of lesions in patients with endometriosis of the rectovaginal septum.

Original languageEnglish
Pages (from-to)485-488
Number of pages4
JournalFertility and Sterility
Volume75
Issue number3
DOIs
Publication statusPublished - 2001

Keywords

  • Intrauterine device
  • Levonorgestrel
  • Rectovaginal endometriosis

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

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