Use of antibiotic prophylaxis in multichannel urodynamics: Is there a rationale?

D. Porru, G. Campus, G. Madeddu, I. Montixi, R. M. Scarpa, E. Usai

Research output: Contribution to journalArticlepeer-review


A total of 100 patients, 52 males and 48 females, were evaluated in the study, and underwent pressure-flow study as part of the diagnostic assessment, after receiving oral antibiotic prophylaxis with norfloxacin 400 mg twice per day. Their clinical condition was bladder outflow obstruction from benign prostatic hyperplasia (BPH) in men, and stress urinary incontinence or voiding dysfunction in women. The incidence of urinary tract infection (UTI), dysuria, and other complications were assessed by screening urine for infection both before and after testing. Mild dysuria was experienced by 33% of patients, with no significant difference between males and females. In 3.8% of men and 4.1% of women post-investigational UTI and fever were found. Six patients reported mild macroscopic haematuria, and in no patient urinary retention or severe complaints were reported after the investigation; no patient required hospitalisation. Post-void residual volume was higher in men with BPH obstruction compared to women. There was no statistically significant relationship between post-void residual volume and post-investigational UTI (p=0.8). We found that objective morbidity rate of invasive urodynamic analysis is low. Mild dysuria is frequently experienced, however severe complications, fever, and haematuria are seldom reported, and the risk of developing post-investigational UTIs is low using antibiotic prophylaxis, both in males and females.

Original languageEnglish
Pages (from-to)196-200
Number of pages5
Issue number4
Publication statusPublished - 1999

ASJC Scopus subject areas

  • Urology


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