In the treatment of status epileptcus (SE), first line drugs are benzodiazepines and others as PHT, that are successful in 80% of the cases. In a pharmacoresistant case of SE the only effective drug was chloral hydrate (IC), usually employed as sedative hypnotic. A girl 13 yrs old presented a severe SE with motor partial seizures secondarily generalised, that continued for more than 30 days despite several first choice treatments. In this period, MRI showed a diffuse cortical laminar necrosis, secondary to the hypoxic damage. No cause of this condition was demonstrated. IC oral administration was followed by a reduction of the seizures > 90% for a period of 6 months.
|Translated title of the contribution||Use of chloral hydrate in a case of pharmacoresistant status epilepticus|
|Number of pages||3|
|Journal||Bollettino - Lega Italiana contro l'Epilessia|
|Publication status||Published - Oct 2002|
ASJC Scopus subject areas
- Clinical Neurology