Use of cryotherapy in the treatment of keloids

L. Rusciani, G. Rossi, R. Bono

Research output: Contribution to journalArticlepeer-review


BACKGROUND. Numerous approaches are used to treat keloids, but none is ideal for all scars and recurrence after treatment is frequent. OBJECTIVE. The purpose of this study was to evaluate the efficacy of cryotherapy for treatment of these scars. METHODS. Sixty-five lesions of various sizes and ages were treated with a hand-held liquid nitrogen spray unit; freeze times and number of sessions varied. Scar volume was measured before and after treatment. RESULTS. Complete flattening was achieved in 48 scars (73%), most of which were less than 2 years old. Unacceptable responses were seen in six scars. No recurrence was seen during follow-ups ranging from 17 to 42 months. Side effects were limited to hypopigmentation and slight to moderate atrophy in three cases. CONCLUSION. Cryotherapy is an effective, low-risk approach to keloid treatment associated with a low rate of recurrence.

Original languageEnglish
Pages (from-to)529-534
Number of pages6
JournalJournal of Dermatologic Surgery and Oncology
Issue number6
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Dermatology
  • Oncology


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