Use of Dithiothreitol to Dislodge Bacteria From the Biofilm on an Aortic Valve in the Operating Theatre: A Case of Infective Endocarditis Caused by Staphylococcus aureus and Proteus mirabilis

Sara G. Rimoldi, Elena De Vecchi, Cristina Pagani, Agostino Zambelli, Annamaria Di Gregorio, Enrica Bosisio, Paolo Vanelli, Roberto Scrofani, Maria R. Gismondo, Giovanni Cagnoni, Carlo Antona

Research output: Contribution to journalArticlepeer-review

Abstract

This is the first reported case of 2 biofilm-producing bacteria, Staphylococcus aureus and Proteus mirabilis, identified from an aortic valve using an innovative device with dithiothreitol solution, able to dislodge bacterial biofilm. The method is usable in the operating theatre and recommended in infective endocarditis nonresponders to empiric therapy.

Original languageEnglish
Pages (from-to)e357-e359
JournalAnnals of Thoracic Surgery
Volume102
Issue number4
DOIs
Publication statusPublished - Oct 1 2016

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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