Use of molecular techniques to confirm true re-emergence of an original clone and to track minimal residual disease in acute lymphoblastic leukemia

A. Valetto, A. Anselmi, F. Scuderi, M. Lanciotti, V. Chiesa, G. Dini

Research output: Contribution to journalArticlepeer-review

Abstract

We report the case of a young girl whose acute lymphoblastic leukemia (ALL) recurred as lymphoblastic lymphoma 6.6 years after diagnosis. Analysis of minimal residual disease (MRD) allowed tracking of the leukemic clone during the phases of therapy, confirming that relapse was a true re-emergence of the original clone.

Original languageEnglish
Pages (from-to)1102-1103
Number of pages2
JournalHaematologica
Volume85
Issue number10
Publication statusPublished - 2000

Keywords

  • Gene rearrangement
  • Late relapse
  • Leukemia
  • T-cell receptor

ASJC Scopus subject areas

  • Hematology

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