Use of nivolumab in elderly patients with advanced squamous non–small-cell lung cancer: results from the Italian cohort of an expanded access programme

Francesco Grossi, Lucio Crinò, Antonio Logroscino, Stefania Canova, Angelo Delmonte, Barbara Melotti, Claudia Proto, Alain Gelibter, Federico Cappuzzo, Daniele Turci, Teresa Gamucci, Paola Antonelli, Paolo Marchetti, Armando Santoro, Sabrina Giusti, Francesco Di Costanzo, Lucio Giustini, Alessandro Del Conte, Lorenzo Livi, Diana GiannarelliFilippo de Marinis

Research output: Contribution to journalArticle

Abstract

Aim: This analysis evaluated the efficacy and safety of nivolumab, an immune checkpoint inhibitor, in elderly patients with stage IIIB or IV squamous non–small-cell lung cancer (NSCLC) enrolled in the expanded access programme (EAP) in Italy. Methods: Nivolumab was available on physician request. Safety data included adverse events (AEs). Efficacy data included investigator-assessed tumour response, progression date and survival information. Results were analysed for patients aged
Original languageEnglish
Pages (from-to)126-134
Number of pages9
JournalEuropean Journal of Cancer
Volume100
DOIs
Publication statusPublished - Sep 1 2018

Keywords

  • Aged
  • Immunotherapy
  • Italy
  • Non–small-cell lung cancer

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    Grossi, F., Crinò, L., Logroscino, A., Canova, S., Delmonte, A., Melotti, B., Proto, C., Gelibter, A., Cappuzzo, F., Turci, D., Gamucci, T., Antonelli, P., Marchetti, P., Santoro, A., Giusti, S., Di Costanzo, F., Giustini, L., Del Conte, A., Livi, L., ... de Marinis, F. (2018). Use of nivolumab in elderly patients with advanced squamous non–small-cell lung cancer: results from the Italian cohort of an expanded access programme. European Journal of Cancer, 100, 126-134. https://doi.org/10.1016/j.ejca.2018.05.015